Mc-Phe-Lys-PAB-MMAE
Based on 1 Customer Validation
Mc-Phe-Lys-PAB-MMAE (Compound 2) is a drug-linker conjugate for ADC, and can be used for synthesis of ADCs.
For research use only. We do not sell to patients.
- CAS No.: 646502-54-7
- Formula: C72H106N10O14
- Molecular Weight:1335.67
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Storage:
-20°C, sealed storage, away from moisture and light
* The compound is unstable in solutions, freshly prepared is recommended.
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 646502-54-7
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Appearance Solid
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Molecular Weight 1335.67
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Formula C72H106N10O14
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Color White to off-white
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SMILES
CN([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)CCC1)=O)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCCN)NC([C@H](CC4=CC=CC=C4)NC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : ≥ 100 mg/mL (74.87 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7487 mL | 3.7434 mL | 7.4869 mL | 18.7172 mL |
| 5 mM | 0.1497 mL | 0.7487 mL | 1.4974 mL | 3.7434 mL | |
| 10 mM | 0.0749 mL | 0.3743 mL | 0.7487 mL | 1.8717 mL | |
| 15 mM | 0.0499 mL | 0.2496 mL | 0.4991 mL | 1.2478 mL | |
| 20 mM | 0.0374 mL | 0.1872 mL | 0.3743 mL | 0.9359 mL | |
| 25 mM | 0.0299 mL | 0.1497 mL | 0.2995 mL | 0.7487 mL | |
| 30 mM | 0.0250 mL | 0.1248 mL | 0.2496 mL | 0.6239 mL | |
| 40 mM | 0.0187 mL | 0.0936 mL | 0.1872 mL | 0.4679 mL | |
| 50 mM | 0.0150 mL | 0.0749 mL | 0.1497 mL | 0.3743 mL | |
| 60 mM | 0.0125 mL | 0.0624 mL | 0.1248 mL | 0.3120 mL |