MC-Val-Cit-Doxorubicin
Based on 1 Customer Validation
MC-Val-Cit-Doxorubicin (MC-Val-Cit-PAB-Doxorubicin) is drug-linker conjugate for ADC. The maleimide can conjugate with thiol containing molecules. Doxorubicin is an anthracycline antibiotic with antineoplastic activity
For research use only. We do not sell to patients.
- Purity: 99.67%
- CAS No.: 159857-70-2
- Formula: C56H67N7O19
- Molecular Weight:1142.17
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 159857-70-2
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Appearance Solid
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Molecular Weight 1142.17
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Formula C56H67N7O19
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Color Brown to red
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SMILES
OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)=O)=C1C[C@](O)(C4)C(CO)=O
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Synonyms
MC-Val-Cit-PAB-Doxorubicin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (87.55 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (246 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.8755 mL | 4.3776 mL | 8.7553 mL | 21.8882 mL |
| 5 mM | 0.1751 mL | 0.8755 mL | 1.7511 mL | 4.3776 mL | |
| 10 mM | 0.0876 mL | 0.4378 mL | 0.8755 mL | 2.1888 mL | |
| 15 mM | 0.0584 mL | 0.2918 mL | 0.5837 mL | 1.4592 mL | |
| 20 mM | 0.0438 mL | 0.2189 mL | 0.4378 mL | 1.0944 mL | |
| 25 mM | 0.0350 mL | 0.1751 mL | 0.3502 mL | 0.8755 mL | |
| 30 mM | 0.0292 mL | 0.1459 mL | 0.2918 mL | 0.7296 mL | |
| 40 mM | 0.0219 mL | 0.1094 mL | 0.2189 mL | 0.5472 mL | |
| 50 mM | 0.0175 mL | 0.0876 mL | 0.1751 mL | 0.4378 mL | |
| 60 mM | 0.0146 mL | 0.0730 mL | 0.1459 mL | 0.3648 mL | |
| 80 mM | 0.0109 mL | 0.0547 mL | 0.1094 mL | 0.2736 mL |
MC-Val-Cit-Doxorubicin Related Classifications
HY-W190927 Related Classifications
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