Methyltetrazine-PEG4-NH-Boc

Name: Methyltetrazine-PEG4-NH-Boc
Brand: MedChemExpress
SKU: HY-141279
Rating: 4.5 (0 reviews)

Cat. No.: HY-141279: Ficha de datos Instrucciones de manejo
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Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

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Methyltetrazine-PEG4-NH-Boc Estructura química

No. CAS : 2194563-84-1

Tamaño	Stock	Cantidad
5 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
500 mg	Obtener un presupuesto
1 g	Obtener un presupuesto

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Based on 1 Customer Validation

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

463.53

Fòrmula

C₂₂H₃₃N₅O₆

No. CAS

2194563-84-1

SMILES

O=C(OC(C)(C)C)NCCOCCOCCOCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]