Microtubule inhibitor 5
Microtubule inhibitor 5 (compound 17f) is a potent microtubule inhibitor. Microtubule inhibitor 5 shows cytotoxicity with an IC50 value of 154.5 nM for NCI-H460 cells. Microtubule inhibitor 5 shows good cell permeability.
For research use only. We do not sell to patients.
- CAS No.: 2416338-55-9
- Formula: C22H15FN2O4
- Molecular Weight:390.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H460 | IC50 |
154.5 nM
Compound: 17f
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Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay
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[PMID: 32278711] |
Chemical Information
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CAS No. 2416338-55-9
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Molecular Weight 390.36
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Formula C22H15FN2O4
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SMILES
O=C1N/C(C(N/C1=C\C2=CC(OC3=CC=C(C=C3)F)=CC=C2)=O)=C\C4=CC=CO4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Microtubule inhibitor 5 Related Classifications
HY-147726 Related Classifications
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