Mitochondrial respiration-IN-3
Mitochondrial respiration-IN-3 is the fluorine derivative of Dalfopristin (HY-A0241). Mitochondrial respiration-IN-3 has cell membrane-permeable. Mitochondrial respiration-IN-3 can inhibit mitochondrial translation of glioblastoma stem cells. Mitochondrial respiration-IN-3 can be used in research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3042814-00-3
- Formula: C34H51FN4O8S
- Molecular Weight:694.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Mitochondrial respiration-IN-3 ((16R)-1e; 48 h; COMI cells) inhibits cell growth with a GI50 value of 6.73 μM[1].
Mitochondrial respiration-IN-3 (100 μM; 3 h; COMI cells) has good cell membrane-permeable and increases permeability compared to Dalfopristin[1].
Mitochondrial respiration-IN-3 (0-5 μM; 48 h; COMI cells) inhibits mitochondrial translation in a dose-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3042814-00-3
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Molecular Weight 694.85
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Formula C34H51FN4O8S
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SMILES
O=S([C@H]1[C@@]2(C(O[C@H](C(C)C)[C@H](C)/C=C/C(NC/C=C/C(C)=C/[C@@H](O)C[C@@H](F)CC3=NC(C(N2CC1)=O)=CO3)=O)=O)[H])(CCN(CC)CC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)