mmu-miR-6240 antagomir
Based on 1 publication(s) in Google Scholar
mmu-miR-6240 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
For research use only. We do not sell to patients.
- Molecular Weight:8669.55
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) mmu-miR-6240 antagomir
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Biological Activity
Description
Chemical Information
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Appearance Solid
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Molecular Weight 8669.55
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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miRBase Accession Number
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Mature miRNA Sequence
CCAAAGCAUCGCGAAGGCCCACGGCG
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Stem-loop ID
mmu-mir-6240
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Stem-loop Sequence
UUGAGAAAAACAAAACCAAAAAACCCCAAAGCAUCGCGAAGGCCCACGGCGGGUGUUGACUCGAUGUGAUUUCUGCCCAGUGCUCUGAAGGUCAAUGUGAAGAAAUGUGACUCUCUU
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Species
Mouse
Publications (1)
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Journal Impact Factor
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Most Recent
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J Ethnopharmacol
Cortex Dictamni induces retinitis pigmentosa in zebrafish by inhibiting pde6a post-transcriptional activity via mmu-mir-6240-p3_2. [Abstract]2025 Jan 31:340:119282. PMID: 39716511
Purity & Documentation
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Data Sheet (230 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)