Mono(2-ethyl-5-hydroxyhexyl) terephthalate

(Synonyms: MEHHTP)
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Mono (2-ethyl-5-hydroxyhexyl) terephthalate (MEHHTP), a hydroxyl metabolite of the phthalate alternative Di-2-ethylhexyl terephthalate (DEHTP), is a liver X receptor α (LXRα) agonist with a binding energy of -7.41 kcal/mol. Mono (2-ethyl-5-hydroxyhexyl) terephthalate upregulates LXRα downstream targets such as SREBP-1c and FASN and increases lipogenic enzyme activity in hepatocytes, and elevating triglyceride (TG) levels. Mono (2-ethyl-5-hydroxyhexyl) terephthalate is promising for research of nonalcoholic fatty liver disease (NAFLD).

For research use only. We do not sell to patients.

  • Purity: 98.27%
  • CAS No.: 1684398-38-6
  • Formula: C16H22O5
  • Molecular Weight:294.34
  • Storage:

    Store at room temperature 3 years.

    In solvent   -80°C, 2 years , -20°C, 1 year
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