Mtb-cyt-bd oxidase-IN-7
Mtb-cyt-bd oxidase-IN-7 is a cytochrome bd terminal oxidase (Cyt-bd) inhibitor with a Kd value of 4.17 μM. Mtb-cyt-bd oxidase-IN-7 shows anti-tuberculosis activities.
For research use only. We do not sell to patients.
- CAS No.: 3037358-09-8
- Formula: C18H14F3NO2
- Molecular Weight:333.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Mtb-cyt-bd oxidase-IN-7 (compound 8d) is a 1-hydroxy-2-methylquinolin-4(1H)-one derivative. Mtb-cyt-bd oxidase-IN-7 inhibits the growth of the cytochrome bcc-aa3 oxidase (Cyt-bcc) knock-out strain (ΔqcrCAB, Cyt-bd+) with a MIC value of 6.25 μM. The combination of Mtb-cyt-bd oxidase-IN-7 with the Cyt-bcc inhibitor Q203 completely inhibited oxygen consumption of the wild-type strain and the inverted-membrane vesicles expressing M. tuberculosis Cyt-bd (ΔcydAB::MtbCydAB+)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3037358-09-8
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Molecular Weight 333.30
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Formula C18H14F3NO2
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SMILES
CC1=C(C(C2=CC=CC=C2N1O)=O)CC3=CC=C(C=C3)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mtb-cyt-bd oxidase-IN-7 Related Classifications
HY-151956 Related Classifications
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