2. Anti-infection
  3. Bacterial
  4. Mtb-IN-3

Mtb-IN-3 (compound 10c) is an inhibitor of Mycobacterium tuberculosis (Mtb). Mtb-IN-3 shows selective, potent in vitro antimycobacterial activity without cytotoxicity. Mtb-IN-3 inhibits colony-forming in spleen in the murine tuberculosis model.

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Mtb-IN-3

Mtb-IN-3 Chemical Structure

CAS No. : 3052302-61-8

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Mtb-IN-3 Related Antibodies

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Description

Mtb-IN-3 (compound 10c) is an inhibitor of Mycobacterium tuberculosis (Mtb). Mtb-IN-3 shows selective, potent in vitro antimycobacterial activity without cytotoxicity. Mtb-IN-3 inhibits colony-forming in spleen in the murine tuberculosis model[1].

IC50 & Target

Mtb[1]
Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
>25 μM
Compound: 10'
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability
[PMID: 37423128]
Masse moléculaire

320.30

Formule

C18H12N2O4
CAS No.
SMILES

O=C(C1=NC2=C(C=CC=C2)C=C1)NC(C=C3)=CC4=C3C(OCO4)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

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Pureté et documentation
Références
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Mtb-IN-3 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mtb-IN-33052302-61-8BacterialInhibitorinhibitorinhibit

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