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Cat. No.: HY-N19873

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Mukurozioside IIa

Mukurozioside IIa is a sesquiterpene glycoside found in S. mukorossi. Mukurozioside IIa can be used for the research of breast cancer.

For research use only. We do not sell to patients.

CAS No.: 103001-35-0
Formula: C₅₁H₈₈O₂₈
Molecular Weight:1149.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Mukurozioside IIa Chemical Structure

CAS No.: 103001-35-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Mukurozioside IIa is a sesquiterpene glycoside found in S. mukorossi. Mukurozioside IIa can be used for the research of breast cancer^[1]^[2].

In Vitro

Mukurozioside IIa moderately inhibits the proliferation of MCF-7, MDA-MB-231, and MDA-MB-435s human breast cancer cells in vitro, with IC₅₀ values ranging from 120.73 to 154.01 μg/mL^[1].
Mukurozioside IIa interacts with 75 predicted breast cancer-related targets, with 22 key shared targets including PTPN1, IL2, and VEGFA^[1].
Mukurozioside IIa (3-100 μM; 44 h) does not inhibit TNF-α-induced cytotoxicity in L929 cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay

Cell Line:

L929 cells
Concentration:

3 μM; 10 μM; 30 μM; 100 μM
Incubation Time:

44 h
Result:

Showed -2.5% inhibition of TNF-α-induced cytotoxicity at 3 μM.
Showed -3.6% inhibition of TNF-α-induced cytotoxicity at 10 μM.
Showed -4.7% inhibition of TNF-α-induced cytotoxicity at 30 μM.
Showed -6.5% inhibition of TNF-α-induced cytotoxicity at 100 μM.
Demonstrated no statistically significant effects relative to the control.

Chemical Information

CAS No. 103001-35-0
Molecular Weight 1149.23
Formula C₅₁H₈₈O₂₈
SMILES

O[C@H]([C@@H]([C@H]([C@@H](O1)C)O)O)[C@@H]1O[C@@H]([C@@H]([C@H](O[C@H]2OC/C=C(C)/CC/C=C(C)/CCCC(C)CO[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)CO)O)[C@H]2O[C@H]6[C@@H]([C@@H]([C@H]([C@@H](O6)C)O)O)O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wei MP, et al. Isolation of two sesquiterpene glycosides from Sapindus mukorossi Gaertn. with cytotoxic properties and analysis of their mechanism based on network pharmacology. Nat Prod Res. 2021 Nov;35(22):4323-4330. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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