2. Natural Products
  3. Plants Terpenoids
  4. Sapindaceae Sesquiterpenes
  5. Sapindus mukorossi Gaertn.
  6. Mukurozioside IIa

Mukurozioside IIa is a sesquiterpene glycoside found in S. mukorossi. Mukurozioside IIa can be used for the research of breast cancer.

For research use only. We do not sell to patients.

Mukurozioside IIa

Mukurozioside IIa Chemical Structure

CAS No. : 103001-35-0

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Mukurozioside IIa Related Antibodies

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Description

Mukurozioside IIa is a sesquiterpene glycoside found in S. mukorossi. Mukurozioside IIa can be used for the research of breast cancer[1][2].

In Vitro

Mukurozioside IIa moderately inhibits the proliferation of MCF-7, MDA-MB-231, and MDA-MB-435s human breast cancer cells in vitro, with IC50 values ranging from 120.73 to 154.01 μg/mL[1].
Mukurozioside IIa interacts with 75 predicted breast cancer-related targets, with 22 key shared targets including PTPN1, IL2, and VEGFA[1].
Mukurozioside IIa (3-100 μM; 44 h) does not inhibit TNF-α-induced cytotoxicity in L929 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mukurozioside IIa Related Antibodies

Cell Viability Assay

Cell Line: L929 cells
Concentration: 3 μM; 10 μM; 30 μM; 100 μM
Incubation Time: 44 h
Result: Showed -2.5% inhibition of TNF-α-induced cytotoxicity at 3 μM.
Showed -3.6% inhibition of TNF-α-induced cytotoxicity at 10 μM.
Showed -4.7% inhibition of TNF-α-induced cytotoxicity at 30 μM.
Showed -6.5% inhibition of TNF-α-induced cytotoxicity at 100 μM.
Demonstrated no statistically significant effects relative to the control.
Molecular Weight

1149.23

Formula

C51H88O28
CAS No.
SMILES

O[C@H]([C@@H]([C@H]([C@@H](O1)C)O)O)[C@@H]1O[C@@H]([C@@H]([C@H](O[C@H]2OC/C=C(C)/CC/C=C(C)/CCCC(C)CO[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)CO)O)[C@H]2O[C@H]6[C@@H]([C@@H]([C@H]([C@@H](O6)C)O)O)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Mukurozioside IIa Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mukurozioside IIa103001-35-0OthersMDA-MB-435sbreast cancerVEGFAMCF-7MDA-MB-231breast cancer cellsPTPN1IL2Inhibitorinhibitorinhibit

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