N-(8-Carboxyoctanoyl)-deacetyl BMS-202
N-(8-Carboxyoctanoyl)-deacetyl BMS-202 is a target protein ligand-linker conjugate. N-(8-Carboxyoctanoyl)-deacetyl BMS-202 contains the target protein PD-1/PD-L1 ligand and a PROTAC linker. N-(8-Carboxyoctanoyl)-deacetyl BMS-202 can be used for the synthesis of PROTAC PD-L1 Degrader-3 (HY-182959).
For research use only. We do not sell to patients.
- Formula: C31H39N3O5
- Molecular Weight:533.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
N-(8-Carboxyoctanoyl)-deacetyl BMS-202 can be used for the synthesis of PROTAC PD-L1 Degrader-3 (HY-182959). PROTAC PD-L1 Degrader-3 is a PD-L1 PROTAC degrader with a Kd value of 0.36 μM. PROTAC PD-L1 Degrader-3 forms a ternary complex with Hsp70 and PD-L1, thereby driving PD-L1 degradation. PROTAC PD-L1 Degrader-3 can be used in cancer research[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 533.66
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Formula C31H39N3O5
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SMILES
COC1=NC(OCC2=C(C(C3=CC=CC=C3)=CC=C2)C)=CC=C1CNCCNC(CCCCCCC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-(8-Carboxyoctanoyl)-deacetyl BMS-202 Related Classifications
HY-182980 Related Classifications
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