N-Mercaptoacetyl-L-histidine
N-Mercaptoacetyl-L-histidine is an angiotensin-converting enzyme (ACE) inhibitor with a target pIC50 of 3.59 M.N-Mercaptoacetyl-L-histidine binds to the zinc-containing active site of ACE, which mediates conversion of angiotensin I to angiotensin II.N-Mercaptoacetyl-L-histidine can be used for the research of hypertension.
For research use only. We do not sell to patients.
- CAS No.: 62404-82-4
- Formula: C8H11N3O3S
- Molecular Weight:229.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
N-Mercaptoacetyl-L-histidine (THIOL12) is an angiotensin-converting enzyme (ACE) inhibitor with a target pIC50 of 3.59 M[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 62404-82-4
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Molecular Weight 229.26
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Formula C8H11N3O3S
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SMILES
SCC(N[C@H](C(O)=O)CC1=CN=CN1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Waller CL, et al. Three-dimensional quantitative structure-activity relationship of angiotesin-converting enzyme and thermolysin inhibitors. II. A comparison of CoMFA models incorporating molecular orbital fields and desolvation free energies based on active-analog and complementary-receptor-field alignment rules. J Med Chem. 1993;36(16):2390-2403. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Mercaptoacetyl-L-histidine Related Classifications
HY-182457 Related Classifications
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