N-Methyl-4-pyridone-3-carboxamide-d₃

Name: N-Methyl-4-pyridone-3-carboxamide-d 3
Brand: MedChemExpress
SKU: HY-113472S
Rating: 4.5 (1 reviews)

製品番号: HY-113472S 純度: 99.63%: Data Sheet SDS COA 取扱説明書
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N-Methyl-4-pyridone-3-carboxamide-d₃ is deuterium labeled N-Methyl-4-pyridone-3-carboxamide.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

N-Methyl-4-pyridone-3-carboxamide-d<sub>3</sub>

N-Methyl-4-pyridone-3-carboxamide-d₃ 構造式

CAS 番号 : 1207384-47-1

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 1122	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 1122	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solid
1 mg	$420	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
5 mg	$1020	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
10 mg	$1650	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of N-Methyl-4-pyridone-3-carboxamide-d₃:

N-Methyl-4-pyridone-3-carboxamide 在庫あり

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•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

N-Methyl-4-pyridone-3-carboxamide-d₃ is deuterium labeled N-Methyl-4-pyridone-3-carboxamide.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

155.17

分子式

C₇H₅D₃N₂O₂

CAS 番号

1207384-47-1

Unlabeled CAS

769-49-3

Appearance

Solid

Color

White to off-white

SMILES

NC(C1=CN(C([2H])([2H])[2H])C=CC1=O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (644.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.4445 mL	32.2227 mL	64.4454 mL
5 mM	1.2889 mL	6.4445 mL	12.8891 mL
10 mM	0.6445 mL	3.2223 mL	6.4445 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.63%

Select Batch:

データシート (271 KB) SDS (252 KB)

COA (249 KB) HNMR (132 KB) RP-HPLC (169 KB) LCMS (103 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.4445 mL	32.2227 mL	64.4454 mL	161.1136 mL
	5 mM	1.2889 mL	6.4445 mL	12.8891 mL	32.2227 mL
	10 mM	0.6445 mL	3.2223 mL	6.4445 mL	16.1114 mL
	15 mM	0.4296 mL	2.1482 mL	4.2964 mL	10.7409 mL
	20 mM	0.3222 mL	1.6111 mL	3.2223 mL	8.0557 mL
	25 mM	0.2578 mL	1.2889 mL	2.5778 mL	6.4445 mL
	30 mM	0.2148 mL	1.0741 mL	2.1482 mL	5.3705 mL
	40 mM	0.1611 mL	0.8056 mL	1.6111 mL	4.0278 mL
	50 mM	0.1289 mL	0.6445 mL	1.2889 mL	3.2223 mL
	60 mM	0.1074 mL	0.5370 mL	1.0741 mL	2.6852 mL
	80 mM	0.0806 mL	0.4028 mL	0.8056 mL	2.0139 mL
	100 mM	0.0644 mL	0.3222 mL	0.6445 mL	1.6111 mL