N,N-Di-(beta-carboethoxyethyl)methylamine
Based on 1 Customer Validation
N,N-Di-(beta-carboethoxyethyl)methylamine is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥95.0%
- CAS No.: 6315-60-2
- Formula: C11H21NO4
- Molecular Weight:231.29
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E747 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6315-60-2
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Appearance Liquid
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Molecular Weight 231.29
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Formula C11H21NO4
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Color Colorless to light yellow
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SMILES
O=C(OCC)CCN(C)CCC(=O)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (432.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3236 mL | 21.6179 mL | 43.2358 mL | 108.0894 mL |
| 5 mM | 0.8647 mL | 4.3236 mL | 8.6472 mL | 21.6179 mL | |
| 10 mM | 0.4324 mL | 2.1618 mL | 4.3236 mL | 10.8089 mL | |
| 15 mM | 0.2882 mL | 1.4412 mL | 2.8824 mL | 7.2060 mL | |
| 20 mM | 0.2162 mL | 1.0809 mL | 2.1618 mL | 5.4045 mL | |
| 25 mM | 0.1729 mL | 0.8647 mL | 1.7294 mL | 4.3236 mL | |
| 30 mM | 0.1441 mL | 0.7206 mL | 1.4412 mL | 3.6030 mL | |
| 40 mM | 0.1081 mL | 0.5404 mL | 1.0809 mL | 2.7022 mL | |
| 50 mM | 0.0865 mL | 0.4324 mL | 0.8647 mL | 2.1618 mL | |
| 60 mM | 0.0721 mL | 0.3603 mL | 0.7206 mL | 1.8015 mL | |
| 80 mM | 0.0540 mL | 0.2702 mL | 0.5404 mL | 1.3511 mL | |
| 100 mM | 0.0432 mL | 0.2162 mL | 0.4324 mL | 1.0809 mL |
N,N-Di-(beta-carboethoxyethyl)methylamine Related Classifications
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