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Cat. No.: HY-152863

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N6-Furfuryl-2-aminoadenosine

N6-Furfuryl-2-aminoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

CAS No.: 26783-39-1
Formula: C₁₅H₁₈N₆O₅
Molecular Weight:362.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

N6-Furfuryl-2-aminoadenosine Chemical Structure

CAS No.: 26783-39-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
Caco-2	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 38280656]
Caco-2	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38280656]
Caco-2	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38280656]
HeLa	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 38280656]
HeLa	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38280656]
HeLa	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38280656]
MCF7	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 38280656]
MCF7	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38280656]
MCF7	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38280656]
MIA PaCa-2	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 38280656]
MIA PaCa-2	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38280656]
MIA PaCa-2	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38280656]
MRC5	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 38280656]
MRC5	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38280656]
MRC5	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38280656]
OVCAR-3	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 38280656]
OVCAR-3	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38280656]
OVCAR-3	IC₅₀	>100 μM Compound: 8; 2-aminoKR	Cytotoxicity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38280656]

Chemical Information

CAS No. 26783-39-1
Molecular Weight 362.34
Formula C₁₅H₁₈N₆O₅
SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=NC(N)=NC(NCC4=CC=CO4)=C3N=C2)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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N6-Furfuryl-2-aminoadenosine

High-Throughput Bioactive Compound Library

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

N6-Furfuryl-2-aminoadenosine Related Classifications

HY-152863 Related Classifications