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Onvuzosiran sodium

Onvuzosiran sodium, a siRNA, is a prekallikrein synthesis reducer.

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  • Formula: C534H661F15N180Na46O329P44S8
  • Molecular Weight:17826.80
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Onvuzosiran sodium Chemical Structure
    Onvuzosiran sodium Chemical Structure
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All Kallikrein Isoforms

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  • Onvuzosiran sodium Chemical Structure
    Onvuzosiran sodium Chemical Structure RNA, ([3'-O-[2-[[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]-2'-O-[2-[bis[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]]C-(5'→5')-sp-Um-sp-Cm-Cm-Am-Gm-Gm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-Um-Gm-Am-Am-Um-Um-Am-Cm-sp-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]A), complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)G-sp-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)G-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)C-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)G-Am-sp-Gm-sp-Um) (1:1), sodium salt
    1/16
  • RNA, ([3'-O-[2-[[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]-2'-O-[2-[bis[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]]C-(5'→5')-sp-Um-sp-Cm-Cm-Am-Gm-Gm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-Um-Gm-Am-Am-Um-Um-Am-Cm-sp-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]A), complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)G-sp-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)G-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)C-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)G-Am-sp-Gm-sp-Um) (1:1), sodium salt