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Cat. No.: HY-170654

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Opioid receptor antagonist 1

Opioid receptor antagonist 1 (Compound 10) is an Orvinol (HY-D0168)-based opioid receptor antagonist. Opioid receptor antagonist 1 has antagonistic activity to the analgesic properties of Morphine.

For research use only. We do not sell to patients.

CAS No.: 1559075-15-8
Formula: C₂₄H₂₉ClF₃NO₄
Molecular Weight:487.94

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Opioid receptor antagonist 1 Chemical Structure

CAS No.: 1559075-15-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

All Opioid Receptor Isoforms :

In Vivo

Opioid receptor antagonist 1 (0.1-10 mg/kg, s.c.) dose-dependently suppresses the analgesic effect of morphine in mice (tail-flick test)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1559075-15-8
Molecular Weight 487.94
Formula C₂₄H₂₉ClF₃NO₄
SMILES

C=CCN1CC[C@@]23C4=C5C(O)=CC=C4C[C@@H]1[C@@]2(CC6)C[C@@]([C@](O)(C)C(F)(F)F)([H])[C@@]6(O)[C@@H]3O5.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ambartsumyan AA, et al. Orvinol-based opioid receptor antagonist fluorinated at C(20)-pharmacophore. Eur J Med Chem. 2024 Dec 18;284:117189. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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