Orexin 2 Receptor Agonist 3
Orexin 2 Receptor Agonist 3 (Compound 57) is an orally active and brain-penetrant orexin receptor type-2 (OX2) agonist (EC50: 2.5 nM). Orexin 2 Receptor Agonist 3 increases wakefulness in the orexin/ataxin-3 NT1 mouse model and healthy beagle dogs. Orexin 2 Receptor Agonist 3 can be used in the study of narcolepsy.
For research use only. We do not sell to patients.
- Formula: C27H29F2N7O3
- Molecular Weight:537.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Orexin Receptor (OX Receptor) Isoforms
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Biological Activity
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OX2 2.5 nM (EC50) |
Chemical Information
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Molecular Weight 537.56
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Formula C27H29F2N7O3
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SMILES
FC1=CC([C@H](C(NC2(C3)CC3(C)C2)=O)N(C4CC5(CC5)C4)C(CC6=C(C7=NN(C)N=N7)ON=C6)=O)=C(F)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)