PCSK9 autophagic degrader 2
Based on 1 publication(s) in Google Scholar
PCSK9 autophagic degrader 2 (W6) is a PCSK9 targeted autophagosome, with an DC50 of 20.6 nM. PCSK9 autophagic degrader 2 (W6) demonstrates comparable antiatherosclerosis effect and exhibits a KD of 2.5 μM for LC3B (Pink: PCSK9 ligand HY-176044; Blue: LC3B ligand HY-176045; Black: linker HY-141373).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2974497-11-3
- Fòrmula: C39H41Br2IN4O8S
- Peso molecular:1012.54
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) PCSK9 autophagic degrader 2
More
Actividad biológica
Chemical Information
-
No. CAS 2974497-11-3
-
Peso molecular 1012.54
-
Fòrmula C39H41Br2IN4O8S
-
SMILES
O=C(NC1=NC=CS1)CC2(C)NCCC3=C2C=C(OCCOCCOCCOCCN4C(/C(C5=C4C=CC(I)=C5)=C/C6=CC(Br)=C(O)C(Br)=C6)=O)C(OC)=C3
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
J Med Chem
PCSK9 Targeted Autophagosome-Tethering Compounds: Design, Synthesis, and Antiatherosclerosis Evaluation. [Abstract]2025 Apr 24;68(8):8190-8207. PMID: 40226893
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PCSK9 autophagic degrader 2 Related Classifications
HY-176043 Related Classifications
Powered by Bioz