country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-118375

Copy Link Print Information

Phenylbutyl isoselenocyanate

(Synonyms: ISC-4)

Phenylbutyl isoselenocyanate (ISC-4) is a selective apoptosis inducer that increases reactive oxygen species levels to inhibit androgen receptor (AR) and activate p53 pathway. Phenylbutyl isoselenocyanate induces apoptosis in LNCaP prostate cancer cells and has anti-prostate cancer properties.

For research use only. We do not sell to patients.

CAS No.: 1072807-15-8
Formula: C₁₁H₁₃NSe
Molecular Weight:238.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Phenylbutyl isoselenocyanate Chemical Structure

CAS No.: 1072807-15-8

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
Caco-2	IC₅₀	12 μM Compound: 2c, ISC-4	Cytotoxicity against human Caco-2 cells after 72 hrs by MTS assay Cytotoxicity against human Caco-2 cells after 72 hrs by MTS assay	[PMID: 19053750]
HT-1080	IC₅₀	11 μM Compound: 2c, ISC-4	Cytotoxicity against human HT1080 cells after 72 hrs by MTS assay Cytotoxicity against human HT1080 cells after 72 hrs by MTS assay	[PMID: 19053750]
MDA-MB-231	IC₅₀	21 μM Compound: 2c, ISC-4	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTS assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTS assay	[PMID: 19053750]
PC-3	IC₅₀	19 μM Compound: 2c, ISC-4	Cytotoxicity against human PC-3 cells after 72 hrs by MTS assay Cytotoxicity against human PC-3 cells after 72 hrs by MTS assay	[PMID: 19053750]
T98G	IC₅₀	27 μM Compound: 2c, ISC-4	Cytotoxicity against human T98G cells after 72 hrs by MTS assay Cytotoxicity against human T98G cells after 72 hrs by MTS assay	[PMID: 19053750]
UACC-903	IC₅₀	10 μM Compound: 2c, ISC-4	Cytotoxicity against human UACC-903 cells after 72 hrs by MTS assay Cytotoxicity against human UACC-903 cells after 72 hrs by MTS assay	[PMID: 19053750]

Chemical Information

CAS No. 1072807-15-8
Molecular Weight 238.19
Formula C₁₁H₁₃NSe
SMILES

[Se]=C=NCCCCC1=CC=CC=C1
Synonyms

ISC-4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote