Phytoene desaturase-IN-1
Based on 1 Customer Validation
Phytoene desaturase-IN-1 is a potent phytoene desaturase (PDS) inhibitor (Kd: 65.9 μM) through π−π stacking effect with Phe301 residue. Phytoene desaturase-IN-1 shows broad spectrum of postemergence herbicidal activity. Phytoene desaturase-IN-1 induces PDS mRNA reduction, phytoene and reactive oxygen species (ROS) accumulation in albino leaves. Phytoene desaturase-IN-1 can be used in the area of agricultural production.
For research use only. We do not sell to patients.
- Purity: 99.59%
- CAS No.: 2765793-54-0
- Formula: C18H13ClF3N3O2S
- Molecular Weight:427.83
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Phytoene desaturase (PDS), reactive oxygen species (ROS)[1].
Phytoene desaturase-IN-1 (1b, 375−750 g/ha, 25 days) shows a broad spectrum of herbicidal activity against six kinds of weeds (including ECHCG, DIGSA, SETFA, ABUJU, AMARE, and ECLPR)[1].
Phytoene desaturase-IN-1 (750 g/ha, 14 days) down-regulates PDS mRNA level and induces phytoene accumulation, with the observed albino leaf phenotype[1].
Phytoene desaturase-IN-1 (750 g/ha, 3 days) induces ROS accumulation and regulates ROS-associated enzymes activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Albino leaves
-
Concentration:750 g/ha
-
Incubation Time:14 days
-
Result:Reduced PDS mRNA level by 30%, thereby limiting the catalytic dehydrogenation process of phytoene and causing phytoene accumulation.
Chemical Information
-
CAS No. 2765793-54-0
-
Appearance Solid
-
Molecular Weight 427.83
-
Formula C18H13ClF3N3O2S
-
Color Off-white to light yellow
-
SMILES
O=C(C1=CC=C(Cl)C=C1)CSC2=NN=C(CO)N2C3=CC=CC(C(F)(F)F)=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (292.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (276 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3374 mL | 11.6869 mL | 23.3738 mL | 58.4344 mL |
| 5 mM | 0.4675 mL | 2.3374 mL | 4.6748 mL | 11.6869 mL | |
| 10 mM | 0.2337 mL | 1.1687 mL | 2.3374 mL | 5.8434 mL | |
| 15 mM | 0.1558 mL | 0.7791 mL | 1.5583 mL | 3.8956 mL | |
| 20 mM | 0.1169 mL | 0.5843 mL | 1.1687 mL | 2.9217 mL | |
| 25 mM | 0.0935 mL | 0.4675 mL | 0.9350 mL | 2.3374 mL | |
| 30 mM | 0.0779 mL | 0.3896 mL | 0.7791 mL | 1.9478 mL | |
| 40 mM | 0.0584 mL | 0.2922 mL | 0.5843 mL | 1.4609 mL | |
| 50 mM | 0.0467 mL | 0.2337 mL | 0.4675 mL | 1.1687 mL | |
| 60 mM | 0.0390 mL | 0.1948 mL | 0.3896 mL | 0.9739 mL | |
| 80 mM | 0.0292 mL | 0.1461 mL | 0.2922 mL | 0.7304 mL | |
| 100 mM | 0.0234 mL | 0.1169 mL | 0.2337 mL | 0.5843 mL |
Phytoene desaturase-IN-1 Related Classifications
HY-151095 Related Classifications
Powered by Bioz