2. JAK/STAT Signaling Apoptosis
  3. Pim Apoptosis
  4. Pim-1 kinase-IN-15

Pim-1 kinase-IN-15 (Compound 15) is a highly potent and selective Pim-1 kinase inhibitor (IC50=0.212 μM). Pim-1 kinase-IN-15 induces tumor cell apoptosis and suppresses cell migration. Pim-1 kinase-IN-15 is promising for research of oncology, such as breast cancer.

For research use only. We do not sell to patients.

Pim-1 kinase-IN-15

Pim-1 kinase-IN-15 Chemical Structure

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Pim-1 kinase-IN-15 Related Antibodies

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Description

Pim-1 kinase-IN-15 (Compound 15) is a highly potent and selective Pim-1 kinase inhibitor (IC50=0.212 μM). Pim-1 kinase-IN-15 induces tumor cell apoptosis and suppresses cell migration. Pim-1 kinase-IN-15 is promising for research of oncology, such as breast cancer[1].

IC50 & Target

PIM1

 

Molecular Weight

483.58

Formula

C27H25N5O2S
SMILES

O=C1N(CC(N/N=C2C(C=CC=C3)=C3CC/2)=O)C=NC4=C1C(CC5)=C(S4)CN5CC6=CC=CC=C6
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pim-1 kinase-IN-15 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pim-1 kinase-IN-15PimApoptosisPim kinasesPim-1 kinasetumor celloncologyInhibitorinhibitorinhibit

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