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Cat. No.: HY-N15070

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Polyozellin

Polyozellin is a prolyl endopeptidase inhibitor. Polyozellin has activities against inflammation, cancer, and oxidative stress-related disorders. .

For research use only. We do not sell to patients.

CAS No.: 197703-46-1
Formula: C₂₂H₁₄O₁₀
Molecular Weight:438.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Polyozellin Chemical Structure

CAS No.: 197703-46-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Polyozellin is a prolyl endopeptidase inhibitor. Polyozellin has activities against inflammation, cancer, and oxidative stress-related disorders. ^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	2 μM Compound: 2	Antiproliferative activity against human HL60 cells Antiproliferative activity against human HL60 cells	[PMID: 29429833]
MCF7	IC₅₀	26.9 μM Compound: 2	Antiproliferative activity against human MCF7 cells Antiproliferative activity against human MCF7 cells	[PMID: 29429833]

Chemical Information

CAS No. 197703-46-1
Molecular Weight 438.34
Formula C₂₂H₁₄O₁₀
SMILES

O=C(C)OC1=C2C3=CC(O)=C(O)C=C3OC2=C(OC4=C5C=C(O)C(O)=C4)C5=C1OC(C)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Na-Hee Jeong, et al. Polyozellin alleviates atopic dermatitis-like inflammatory and pruritic responses in activated keratinocytes and mast cells. Biomed Pharmacother. 2020 Feb:122:109743. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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