Pomalidomide-C3-NHS ester

Cat. No.: HY-148142 Purity: 98.70%: Data Sheet
COA

SDS
Handling Instructions
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Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Pomalidomide-C3-NHS ester 화학구조

CAS No. : 2828476-87-3

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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•Related Small Molecules:

•Related Proteins:

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

View All Isoforms

von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

Biological Activity
순도&문서
고객리뷰

제품 설명

Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker.

IC₅₀ & Target

Cereblon

분자량

456.41

화학식

C₂₁H₂₀N₄O₈

CAS No.

2828476-87-3

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=C2C=CC=C1NCCCC(ON3C(CCC3=O)=O)=O)N(C4C(NC(CC4)=O)=O)C2=O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

DMSO : 100 mg/mL (219.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1910 mL	10.9551 mL	21.9101 mL
5 mM	0.4382 mL	2.1910 mL	4.3820 mL
10 mM	0.2191 mL	1.0955 mL	2.1910 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.70%

Select Batch:

Data Sheet (243 KB) SDS (251 KB)

COA (250 KB) HNMR (145 KB) RP-HPLC (169 KB) LCMS (107 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1910 mL	10.9551 mL	21.9101 mL	54.7753 mL
	5 mM	0.4382 mL	2.1910 mL	4.3820 mL	10.9551 mL
	10 mM	0.2191 mL	1.0955 mL	2.1910 mL	5.4775 mL
	15 mM	0.1461 mL	0.7303 mL	1.4607 mL	3.6517 mL
	20 mM	0.1096 mL	0.5478 mL	1.0955 mL	2.7388 mL
	25 mM	0.0876 mL	0.4382 mL	0.8764 mL	2.1910 mL
	30 mM	0.0730 mL	0.3652 mL	0.7303 mL	1.8258 mL
	40 mM	0.0548 mL	0.2739 mL	0.5478 mL	1.3694 mL
	50 mM	0.0438 mL	0.2191 mL	0.4382 mL	1.0955 mL
	60 mM	0.0365 mL	0.1826 mL	0.3652 mL	0.9129 mL
	80 mM	0.0274 mL	0.1369 mL	0.2739 mL	0.6847 mL
	100 mM	0.0219 mL	0.1096 mL	0.2191 mL	0.5478 mL