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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
123 Results for "
rankl
" in MedChemExpress (MCE) Product Catalog:
Products (123)
123 Results for "rankl" in MCE Product Catalog:
24
24 Publications Verification
Cat. No.: HY-N0751
CAS No.: 27740-01-8
17
11
11 Cited Publications
Synonyms: 4-Iodo-6-phenylpyrimidine
Research Areas:
4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF) .
10
8
8 Cited Publications
7
6
Target:
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Thonzonium bromide is an antibacterial agent that is structurally similar to Farnesol (HY-Y0248A). Thonzonium bromide is also a monocationic surface-active agent, which inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo. Thonzonium bromide inhibits proton transport in a dose-dependent manner (EC50=69 μM) .
6
6
6 Cited Publications
Cat. No.: HY-N0762
CAS No.: 31524-62-6
4
Category:
Flavonoids Ginkgoaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Ginkgo biloba Biflavones
Target:
4
4 Cited Publications
Research Areas:
NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research .
4
3
Target:
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3
3 Cited Publications
Target:
Research Areas:
VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. VUF11207 fumarate reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation .
3
3 Cited Publications
Cat. No.: HY-P9958A
CAS No.: 615258-40-7
Target:
Research Areas:
2
Category:
Alkaloids Other Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Disease Research Fields Cancer
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2
2 Cited Publications
Cat. No.: HY-N1419
CAS No.: 53452-16-7
2
2 Cited Publications
Cat. No.: HY-W008634
CAS No.: 56741-95-8
Synonyms: U-54461; U-54461S; PNU-54461
Target:
Research Areas:
Bropirimine (U-54461; U-54461S; PNU-54461) is an orally active TLR7 agonist. Bropirimine inhibits RANKL-induced osteoclast differentiation of mouse bone marrow-derived macrophages (BMMs). Bropirimine exhibits dose-dependent direct inhibitory effects on colony formation of cultured KK-47 and 724 cells. Bropirimine can be used for the study of cancers and bone metabolic disorders such as osteoporosis .
2
2
Category:
Simple Phenylpropanols Other Diseases Scrophulariaceae Phenylpropanoids Plants Disease Research Fields Brandisia hancei Hook. f.
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
