1912422-56-0
Chemical Structure
NFATc1-IN-1
- CAS No.: 1912422-56-0
- Formula:C13H8F2INO2
- Molecular Weight:375.11
IUPAC Name: 5-fluoro-N-(2-fluoro-4-iodophenyl)-2-hydroxybenzamide
InChIKey: IGRCFOGPIJEESA-UHFFFAOYSA-N
SMILES: OC1=C(C(NC2=C(F)C=C(I)C=C2)=O)C=C(F)C=C1
Biological Activity: NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research[1].
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NFATc1-IN-1 | 99.97% | NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research. | ||||||||||||||||||||
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Keywords