1912422-56-0
1912422-56-0
Chemical Structure
NFATc1-IN-1
- CAS No.: 1912422-56-0
- Formula:C13H8F2INO2
- Molecular Weight:375.11
IUPAC Name: 5-fluoro-N-(2-fluoro-4-iodophenyl)-2-hydroxybenzamide
InChIKey: IGRCFOGPIJEESA-UHFFFAOYSA-N
SMILES: OC1=C(C(NC2=C(F)C=C(I)C=C2)=O)C=C(F)C=C1
Biological Activity: NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NFATc1-IN-1 | 99.97% | NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-124958NDMC101 -
Similarity Score 0.74
HY-144767PA3552-IN-1 -
Similarity Score 0.67
HY-144771SARS-CoV-2-IN-14 -
Similarity Score 0.67
HY-169055SARS-CoV-2 Mpro-IN-25 -
Similarity Score 0.66
HY-W7064663',5,5'-Trichlorosalicylanilide -
Similarity Score 0.66
HY-B2140Multifungin -
Similarity Score 0.66
HY-15393VU 0357121 -
Similarity Score 0.66
HY-B0497RNiclosamide (Standard) -
Similarity Score 0.66
HY-B0497S1Niclosamide-13C6 -
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