1. Recombinant Proteins
  2. ACE2 Protein, Human (HEK 293, His-Avi)

ACE2 Protein, Human (HEK 293, His-Avi)

Cat. No.: HY-P70769
Handling Instructions

ACE2 Protein, Human (HEK 293, His-Avi) is a metallopeptidase which binds effectively to the S1 domain of the SARS‐CoV protein. ACE2 Protein, Human is also an essential regulator of cardiac function and blood pressure control.

For research use only. We do not sell to patients.

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  • Technical Parameters

  • Properties

  • Documentation

Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2



HEK 293



Gene ID


Molecular Weight

110-140 kDa

AA Sequence



Greater than 95% as determined by reducing SDS-PAGE.

Biological Activity
2 μg/mL (100 μL/well) of immobilized 2019-nCoV S Protein RBD-SD1-mFc can bind Human ACE-2-Avi-His with an ED50 value of 46.47 ng/mL.



Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 1 mM ZnCl2, 10% Glycerol, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C. It is stable at -20℃ for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.


Shipping with dry ice.


Angiotensin‐converting enzyme 2 (ACE2), a metallopeptidase, is the functional receptor for SARS‐CoV. ACE2 can be immunoprecipitated by the S1 domain of the SARS‐CoV virus and that ACE2 can promote viral replication. ACE2 is abundantly present in humans in the epithelia of lung and small intestine, which might provide possible routes of entry for the SARS‐CoV. ACE2, previously identified as the cellular receptor for SARS-CoV, also acts as a receptor of the new coronavirus (SARS-CoV-2). ACE2 is also thought to be an essential regulator of cardiac function and blood pressure control, possibly by acting as a natural counterpart of ACE1[1][2].

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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ACE2 Protein, Human (HEK 293, His-Avi)
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