ACE2 - angiotensin converting enzyme 2 Gene

Also Known as ACEH

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 59272

About ACE2

Cytogenetic location: Xp22.2 Genomic coordinates (GRCh38): X:15,518,197-15,607,211 (from NCBI)

This gene has 11 transcripts (splice variants), 201 orthologues and 1 paralogue. Biased expression in small intestine (RPKM 93.7), duodenum (RPKM 69.0) and 5 other tissues.

Summary

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible. [provided by RefSeq, Nov 2020]

ACE2 Products (6)

mRNA	Protein	Name
NM_001371415.1	NP_001358344.1	angiotensin-converting enzyme 2 isoform 1 precursor
NM_001386259.1	NP_001373188.1	angiotensin-converting enzyme 2 isoform 2 precursor
NM_001386260.1	NP_001373189.1	angiotensin-converting enzyme 2 isoform 3 precursor
NM_001388452.1	NP_001375381.1	angiotensin-converting enzyme 2 isoform 4
NM_001389402.1	NP_001376331.1	angiotensin-converting enzyme 2 isoform 3 precursor
NM_021804.3	NP_068576.1	angiotensin-converting enzyme 2 isoform 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
NOT enables carboxypeptidase activity	IDA IDA: Inferred from direct assay	33077916	GOA
enables carboxypeptidase activity	IDA IDA: Inferred from direct assay	10924499	GOA
enables endopeptidase activity	IDA IDA: Inferred from direct assay	15283675	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	32275855	GOA
enables metallopeptidase activity	IDA IDA: Inferred from direct assay	10924499	GOA
enables peptidyl-dipeptidase activity	IDA IDA: Inferred from direct assay	10924499	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10969042	GOA
NOT enables virus receptor activity	IDA IDA: Inferred from direct assay	33077916	GOA
enables virus receptor activity	IDA IDA: Inferred from direct assay	16051304	GOA
enables virus receptor activity	IMP IMP: Inferred from mutant phenotype	24227843	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in angiotensin-mediated drinking behavior	IMP IMP: Inferred from mutant phenotype	18258853	GOA
involved in entry receptor-mediated virion attachment to host cell	IDA IDA: Inferred from direct assay	36228039	GOA
acts upstream of negative regulation of signaling receptor activity	IMP IMP: Inferred from mutant phenotype	18258853	GOA
involved in positive regulation of L-proline import across plasma membrane	IGI IGI: Inferred from genetic interaction	25534429	GOA
involved in positive regulation of amino acid transport	IMP IMP: Inferred from mutant phenotype	19185582	GOA
involved in positive regulation of gap junction assembly	IMP IMP: Inferred from mutant phenotype	12967627	GOA
involved in receptor-mediated virion attachment to host cell	IDA IDA: Inferred from direct assay	18343844	GOA
involved in regulation of cardiac conduction	IMP IMP: Inferred from mutant phenotype	12967627	GOA
involved in regulation of systemic arterial blood pressure by renin-angiotensin	IMP IMP: Inferred from mutant phenotype	18258853	GOA
involved in regulation of transmembrane transporter activity	IGI IGI: Inferred from genetic interaction	25534429	GOA
acts upstream of positive effect symbiont entry into host cell	IDA IDA: Inferred from direct assay	33163980	GOA
involved in symbiont entry into host cell	IDA IDA: Inferred from direct assay	16051304	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	25534429	GOA
located in brush border membrane	IDA IDA: Inferred from direct assay	25534429	GOA
located in cell surface	IDA IDA: Inferred from direct assay	18343844	GOA
located in extracellular region	IDA IDA: Inferred from direct assay	10969042	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	18258853	GOA
is active in plasma membrane	IDA IDA: Inferred from direct assay	33163980	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	21068237	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACE2 Protein Structure

Peptidase_M2

0
200
400
600
805 a.a.

Protein Preferred Names	Protein Names
angiotensin-converting enzyme 2	ACE-related carboxypeptidase

ACE2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ACE2	Q9BYF1	SFTPD	Homo sapiens	P35247	Solid Phase Assay	33784482
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	Affinity Chrom	15791205
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	FACS	32275855
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	FACS	15791205
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	Confocal	32275855
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	EM	30102747
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	X-Ray Diffraction	22291007
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	ELISA	32203189
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	SPR	21411533
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	Anti Tag CoIP	15791205
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	FACS	32203189
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	Confocal	32203189
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	GMS	30356097
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	SPR	22291007
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	SPR	32275855
Cross	ACE2	Q9BYF1	S	Human SARS coronavirus	P59594	GMS	30102747
Cross	ACE2	Q9BYF1	S	Human coronavirus NL63	Q6Q1S2	SPR	21411533
Intra	ACE2	Q9BYF1	SNX27	Homo sapiens	Q96L92	FPS	33436498
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	FACS	32275855
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	Confocal	32275855
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	ELISA	32753755
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	Pull Down	32917722
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	Solid Phase Assay	32958580
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	BLI	32437749
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	SPR	32275855
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	BLI	32415260
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	FACS	32203189
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	Confocal	32203189
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	X-Ray Diffraction	32275855
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	SLCA	32678978
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	ELISA	32415260
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	ELISA	32203189
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	Solid Phase Assay	32415260
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	3D-EM	32132184
Intra	ACE2	Q9BYF1	S	SARS-CoV-2	P0DTC2	SPR	32225176
Cross	ACE2	Q9BYF1	P59594-PRO_0000037209	Human SARS coronavirus	P59594-PRO_0000037209	GMS	30102747
Intra	ACE2	Q9BYF1	SLC6A19	Homo sapiens	Q695T7	3D-EM	32132184
Intra	ACE2	Q9BYF1	SLC6A19	Homo sapiens	Q695T7	GMS	32132184
Intra	ACE2	Q9BYF1	SLC6A19	Homo sapiens	Q695T7	Anti Tag CoIP	34189428
Cross	ACE2	Q9BYF1	P0DTC2-PRO_0000449647	SARS-CoV-2	P0DTC2-PRO_0000449647	ELISA	34360989
Intra	ACE2	Q9BYF1	P01019-PRO_0000032457	Homo sapiens	P01019-PRO_0000032457	Protease Assay	10969042
Intra	ACE2	Q9BYF1	P01019-PRO_0000032457	Homo sapiens	P01019-PRO_0000032457	Protease Assay	11815627
Cross	ACE2	Q9BYF1	S	bat coronavirus RaTG13	EBI-25496413	ELISA	34824253
Cross	ACE2	Q9BYF1	S	SARS coronavirus PC4-145	Q5GDB5	FACS	15791205
Intra	ACE2	Q9BYF1	Q01523-PRO_0000417390	Homo sapiens	Q01523-PRO_0000417390	BLI	32437749
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6M3G9R1	GMS	34018203
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6M3G9R1	FACS	34018203
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6M3G9R1	3D-EM	34018203
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6M3G9R1	SPR	34018203
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6G6A1M4	3D-EM	34018203
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6G6A1M4	FACS	34018203
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6G6A1M4	GMS	34018203
Cross	ACE2	Q9BYF1	S	Pangolin coronavirus	A0A6G6A1M4	SPR	34018203
Intra	ACE2	Q9BYF1	AP2M1	Homo sapiens	Q96CW1	FPS	33436498
Intra	ACE2	Q9BYF1	SHANK1	Homo sapiens	Q9Y566	FPS	33436498
Intra	ACE2	Q9BYF1	PDZK1	Homo sapiens	Q5T2W1	FPS	33436498
Intra	ACE2	Q9BYF1	VIM	Homo sapiens	P08670	Anti Bait CoIP	35078919
Intra	ACE2	Q9BYF1	VIM	Homo sapiens	P08670	Solid Phase Assay	35078919
Intra	ACE2	Q9BYF1	VIM	Homo sapiens	P08670	Confocal	35078919
Intra	ACE2	Q9BYF1	VIM	Homo sapiens	P08670	Anti Tag CoIP	35078919
Intra	ACE2	Q9BYF1	HSPA5	Homo sapiens	P11021	Anti Tag CoIP	34615619
Intra	ACE2	Q9BYF1	HSPA5	Homo sapiens	P11021	Crosslink	34615619
Intra	ACE2	Q9BYF1	P01019-PRO_0000032458	Homo sapiens	P01019-PRO_0000032458	Cleavage	33453855
Intra	ACE2	Q9BYF1	P01019-PRO_0000032458	Homo sapiens	P01019-PRO_0000032458	Protease Assay	11815627
Intra	ACE2	Q9BYF1	P01042-PRO_0000006688	Homo sapiens	P01042-PRO_0000006688	Protease Assay	11815627
Intra	ACE2	Q9BYF1	P01042-PRO_0000006688	Homo sapiens	P01042-PRO_0000006688	Cleavage	33453855
Intra	ACE2	Q9BYF1	P01042-PRO_0000006688	Homo sapiens	P01042-PRO_0000006688	Protease Assay	10969042
Intra	ACE2	Q9BYF1	P30990-PRO_0000019524	Homo sapiens	P30990-PRO_0000019524	Protease Assay	10969042
Intra	ACE2	Q9BYF1	P30990-PRO_0000019524	Homo sapiens	P30990-PRO_0000019524	Protease Assay	11815627
Intra	ACE2	Q9BYF1	KDM1A	Homo sapiens	O60341	FACS	34031383
Intra	ACE2	Q9BYF1	KDM1A	Homo sapiens	O60341	Demethylase Assay	34031383
Intra	ACE2	Q9BYF1	KDM1A	Homo sapiens	O60341	Confocal	34031383
Intra	ACE2	Q9BYF1	P05067-PRO_0000000092	Homo sapiens	P05067-PRO_0000000092	ELISA	34360989
Intra	ACE2	Q9BYF1	P05067-PRO_0000000092	Homo sapiens	P05067-PRO_0000000092	Confocal	34360989

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ACE2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7441	ACE2 Protein, Human (HEK293, His, solution)	Q9BYF1-1 (Q18-S740)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P7442	ACE2 Protein, Human (HEK293, hFc, solution)	Q9BYF1-1 (Q18-S740)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P7443	ACE2 Protein, Human (HEK293, mFc)	Q9BYF1-1 (Q18-S740)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P70769	ACE2 Protein, Human (Biotinylated, HEK293, His-Avi)	Q9BYF1-1 (Q18-S740)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73489	ACE2 Protein, Human (HEK293, His)	Q9BYF1-1 (Q18-S740)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72807	ACE2 Protein, Human (Biotinylated, sf9, His-Avi)	Q9BYF1-1 (Q18-S740)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P72808	ACE2 Protein, Human (sf9, His)	Q9BYF1-1 (Q18-S740)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P78055	ACE2 Protein, Human (Biotinylated, HEK293, Fc-Avi)	Q9BYF1-1 (Q18-S740)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P700455	ACE2 Protein, Human (Biotinylated, HEK293, mFc-Avi)	Q9BYF1-1 (Q18-S740)	≥ 90%, as determined by reducing SDS-PAGE.

ACE2 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80003	ACE2 Antibody (YA647)	WB, IHC-P, ICC/IF, IP, IF-Tissue	Human, Mouse, Rat, Hamster
HY-P85784	ACE2 Antibody (YA5476)	WB, IHC-P, ICC/IF	Human, Mouse, Rat
HY-P86468	ACE2 Antibody (YA6160)	WB, IHC-P, ICC/IF, IP, ELISA	Human

Related Diseases

Diseases	Alias
Covid-19	2019 Novel Coronavirus 2019-Ncov Infection Covid19 Sars-Cov-2 Infection Wuhan Coronavirus Infection Wuhan Seafood Market Pneumonia Virus Infection
Severe Acute Respiratory Syndrome	Sars Sars-Cov Infection Sars-1 Sar Deficiency Sars - [Severe Acute Respiratory Syndrome]
Hartnup Disorder	Hartnup Disease HND Neutral 1 Amino Acid Transport Defect Neutral Amino Acid Transport Defect Deficiency Of Tryptophan Oxygenase Hartnup'S Disease Aminoaciduria, Hartnup Type Disorder Of Neutral Amino Acid Transport
Long Covid	Post-Acute Sequelae Of Sars-Cov-2 Infection Chronic Covid-19 Pasc Post-Covid Syndrome
Coronavirus Infectious Disease
Viral Pneumonia	Pneumonia, Viral Acute Viral Pneumonia Bronchopneumonia Due To Viruses Other Than Influenza Viruses Interstitial Viral Pneumonia Viral Bronchopneumonia Viral Double Pneumonia Viral Lobar Pneumonia Viral Purulent Pneumonia Virus Interstitial Pneumonia Virus Lobar Pneumonia
Ebola Hemorrhagic Fever	Ebola Virus Disease Viral Hemorrhagic Fever Hemorrhagic Fever, Ebola Ebola Ehf Ebola Fever Hemorrhagic Fevers, Viral Ebola Haemorrhagic Fever Ebod - [Ebola Disease] Evd - [Ebola Virus Disease] Ebola Virus Haemorrhagic Fever Vhf - [Viral Haemorrhagic Fever] Nos Viral Haemorrhagic Fever, Not Otherwise Specified
Critical Covid-19
Non-Severe Covid-19
Avian Influenza	Bird Flu Influenza In Birds Avian Flu
Acute Hemorrhagic Conjunctivitis	Viral Conjunctivitis Conjunctivitis, Acute Hemorrhagic Apollo Disease Epidemic Hemorrhagic Conjunctivitis Viral Conjunctiva Disorder Viral Conjunctivitis Nos
Croup	Acute Obstructive Laryngitis Laryngotracheobronchitis Acute Laryngotracheobronchitis Croup Syndrome Acute Laryngitis With Obstruction Obstructive Laryngitis Obstructive Laryngitis Nos Obstructive Laryngotracheitis Nos
Severe Covid-19
Acute Pulmonary Heart Disease
Critical Illness Polyneuropathy	Polyneuropathy, Critical Illness
Miller Fisher Syndrome	Cranial Variant Of Gbs Fisher'S Syndrome Miller-Fisher Variant Of Guillain-Barre Syndrome Miller-Fisher Syndrome Cranial Variant Of Guillain-Barré Syndrome Cranial Variant Of Guillain-Barre Syndrome Fisher Syndrome
Acute Cor Pulmonale
Inflammatory And Toxic Neuropathy
Conjunctival Disease	Conjunctival Diseases Conjunctival Disorder
Acute Necrotizing Encephalitis	Acute Necrotizing Encephalopathy Postinfectious Acute Necrotizing Hemorrhagic Encephalopathy Ane Acute Necrotizing Encephalopathy Type 1 Adane Ane1 Autosomal Dominant Acute Necrotizing Encephalopathy Iiae3 Susceptibility To Acute Necrotizing Encephalopathy Susceptibility To Infection-Induced Acute Encephalopathy Encephalopathy, Acute Necrotizing, Susceptibility To Encephalitis, Acute Necrotizing
Influenza	Flu Influenza With Non-Respiratory Manifestation Influenza With Other Manifestations Influenza, Human Influenza, Susceptibility To Seasonal Influenza, Virus Identified
Meconium Aspiration Syndrome	Neonatal Aspiration Of Meconium Meconium Aspiration Mas Meconium Aspiration Syndrome Of Newborn Meconium Inhalation Mas - [Meconium Aspiration Syndrome] Meconium Aspiration Nos Meconium Aspiration Syndrome Nos Meconium Pneumonitis Meconium Stained Liqueur Aspiration
Orchitis	Inflammation Of Testis Orchititis Mumps Orchitis
Nephrosclerosis	Renal Sclerosis
Mesenteric Lymphadenitis	Mesenteric Adenitis
Pulmonary Embolism	Pulmonary Artery Embolism Pulmonary Embolus Pulmonary Emboli
Von Economo'S Disease	Encephalitis Lethargica Von Economo Encephalitis Von Economo Disease
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Pneumonia	Acute Pneumonia Pneumonias Infectious Pneumonia Pn - [Pneumonia] Lobar Pneumonia Nos Multifocal Pneumonia Orthostatic Pneumonia Pneumonia Nos Chronic Pneumonia Nos Atypical Pneumonia Passive Pneumonia Purulent Pneumonia Interstitial Lobar Pneumonia Pneumonia, Unspecified Pneumonia Due To Chlamydia Pneumonia Due To Chlamydia Pneumoniae Pneumonia Due To E. Coli Escherichia Coli Lobar Pneumonia Pneumonia Due To H. Influenzae Pneumonia Due To Hemophilus Influenzae Bronchopneumonia Due To H. Influenzae Haemophilus Influenzae Lobar Pneumonia Bronchopneumonia Due To Hemophilus Influenzae Pseudomonal Pneumonia Pseudomonas Pneumonia Pseudomonas Lobar Pneumonia Staphylococcal Pneumonia Staphylococcus Pneumonia Acute Staphylococcal Pneumonia Staphylococcal Double Pneumonia Staphylococcal Lobar Pneumonia Staphylococcal Purulent Pneumonia Staphylococcal Bronchopneumonia Pneumococcal Pneumonia Pneumococcus Pneumonia Bronchopneumonia Due To S. Pneumoniae Pneumococcal Lobar Pneumonia Streptococcal Pneumoniae Pneumonia Streptococcus Pneumoniae Lobar Pneumonia Pyemic Pneumococcal Embolism With Pneumonia Bronchopneumonia Due To Streptococcus Pneumoniae Pneumonia Due To Streptococcus, Group B Group B Streptococcal Pneumonia Adenovirus Pneumonia Adenoviral Pneumonia Adenovirus Viral Pneumonia Pneumonia Respiratory Syncytial Viral Parainfluenza Viral Pneumonia Parainfluenzal Pneumonia Parainfluenza Virus Pneumonia Human Metapneumovirus Pneumonia Human Metapneumovirus Infection Resulting In Pneumonia Pneumocystis Pneumonia Plasma Cells Pneumonia
Viral Exanthem	Viral Rash Nos Virus Exanthema Nonspecific Exanthematous Viral Infection Nonspecific Viral Exanthem Nonspecific Viral Rash Viral Enanthema Nos Viral Disease Characterised By Exanthem Viral Exanthemata Viral Exanthem, Unspecified Viral Exanthema Nos
Pulmonary Artery Disease	Abnormality Of The Pulmonary Artery
Extrinsic Cardiomyopathy
Macrophage Activation Syndrome
Herpangina	Vesicular Pharyngitis
Acute Interstitial Pneumonia	Acute Interstitial Pneumonitis Hamman-Rich Syndrome Accelerated Interstitial Pneumonia Aip Hamman-Rich Disease Idiopathic Pulmonary Fibrosis, Acute Fatal Form Idiopathic Pulmonary Fibrosis
Acute Myocarditis
Acute Disseminated Encephalomyelitis	Acute Disseminated Encephalitis Adem Ade Encephalomyelitis Acute Disseminated Encephalomyelitis, Acute Disseminated Adem - [Acute Disseminated Encephalomyelitis]
Acute Hemorrhagic Encephalitis
Bell'S Palsy	Bell Palsy Facial Nerve Palsy Facial Palsy Facial Paralysis Bell'S Palsy Antoni'S Palsy Facial Cranial Nerve Paralysis Idiopathic Facial Palsy Refrigeration Palsy Facial Nerve Paralysis Seventh Cranial Nerve Paralysis Face Paralysis Nos
Pericardium Disease
Kidney Disease	Renal Failure Kidney Failure Kidney Diseases Nephropathy Abnormality Of The Kidney Impaired Renal Function Disease Renal Anomaly Kidney Dysfunction Renal Disease Nephropathies Renal Failure Adverse Event Abnormal Renal Function
Chickenpox	Varicella Varicella Nos
Common Cold	Acute Coryza Acute Nasopharyngitis Acute Rhinitis Acute Viral Rhinopharyngitis Nasopharyngitis - Acute Nasopharyngitis, Acute Rhino-Sinusitis Rhinosinusitis Common Colds Acute Infective Rhinitis Cold Coryza Head Cold Infective Nasopharyngitis Rhinopharyngitis Acute Nasal Catarrh Infective Rhinitis Acute Nasopharyngeal Catarrh Infective Nasopharyngitis Nos Nasopharyngitis Nos Epipharyngitis Mucositis Nos Inflammatory Disease Of Mucous Membrane Mucosal Inflammation
Subacute Thyroiditis	Giant-Cell Thyroiditis Granulomatous Thyroiditis Subacute Granulomatous Thyroiditis De Quervain'S Thyroiditis Thyroiditis Subacute Thyroiditis, Subacute Pseudogranulomatous Thyroiditis De Quervain Thyroiditis Nonsuppurative Subacute Thyroiditis Pseudotuberculous Thyroiditis Nonsuppurative Thyroiditis Nos
Congestive Heart Failure	Congestive Heart Disease Heart Failure Cardiac Failure Congestive Chf Weak Heart Heart Failure Congestive Ccf - [Congestive Cardiac Failure] Chf - [Congestive Heart Failure] Congestive Cardiac Diseases Congested Heart Failure Congestive Cardiac Failure Cardiac Anasarca Cardiac Oedema Cardiac Stasis Cardiovascular Oedema Cardiac Hydrops Congestive Failure Heart Congestion Heart Fluid Oedematous Heart
Viral Infectious Disease	Viral Disease Arbovirus Infections Virus Infection Virus Diseases Viral Infection Viral Infections Virus Infections
Acute Kidney Tubular Necrosis	Acute Tubular Necrosis Acute Renal Failure With Tubular Necrosis Acute Tubule Necrosis Acute Renal Failure With Lesion Of Tubular Necrosis Atn - Acute Tubular Necrosis Tubular Necrosis Acute Kidney Tubular Necrosis, Acute Acute Renal Tubular Necrosis Acute Tubular Nephrosis Ischaemic Acute Tubular Necrosis Ischaemic Tubular Necrosis Kidney Tubular Necrosis Lower Nephron Nephrosis Necrotising Renal Oedema Renal Tubular Necrosis Toxic Tubular Necrosis Tubular Kidney Necrosis Tubular Necrosis Nos Tubular Nephrosis
Acute Conjunctivitis
Acalculous Cholecystitis	Acute Cholecystitis Without Calculus Acute Acalculous Cholecystitis Cholecystitis Without Calculus
Middle East Respiratory Syndrome	Mers Mers - [Middle East Respiratory Syndrome]
Tracheitis	Acute Tracheitis Chronic Tracheitis Bacterial Tracheitis Acute Tracheitis Nos Tracheitis Nos Tracheal Inflammation
Febrile Seizures, Familial, 5	FEB5 Familial Febrile Seizures 5 Convulsions, Familial Febrile, 5 Familial Febrile Convulsions 5 Febrile Convulsions, Familial, 5
Postural Orthostatic Tachycardia Syndrome	Irritable Heart Mitral Valve Prolapse Syndrome Neurocirculatory Asthenia Orthostatic Intolerance Due To Net Deficiency Familial Orthostatic Tachycardia Due To Norepinephrine Transporter Deficiency Orhtostatic Intolerance Postural Tachycardia Syndrome Due To Net Deficiency Soldiers Heart
West Nile Encephalitis	West-Nile Encephalitis West Nile Fever West Nile Fever Encephalitis West Nile Fever With Encephalitis West-Nile Fever Encephalitis, West Nile Fever
Bronchopneumonia	Lobular Pneumonia Bronchial Pneumonia Chest Infection - Bronchopneumonia
Cardiovascular System Disease	Abnormality Of The Cardiovascular System Cardiovascular Disease Disease Of Subdivision Of Hemolymphoid System Disorder Of Cardiovascular System Cardiovascular Diseases
Transverse Myelitis	Myelitis Transverse Myelitis, Transverse
Viral Encephalitis	Epidemic Encephalitis Encephalitis Viral Encephalitis, Arbovirus Arbovirus Encephalitis Postviral Encephalitis Nos Equine Encephalitis Tick-Borne Encephalitis Viral Encephalitis Transmitted By Tick Mosquito-Borne Encephalitis Acute Haemorrhagic Encephalitis Acute Idiopathic Encephalitis Chronic Viral Encephalitis Endemic Encephalitis Subacute Viral Encephalitis Viral Haemorrhagic Encephalitis Viral Nonepidemic Encephalitis Nonepidemic Encephalitis
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Multisystem Inflammatory Syndrome In Children	Mis-C Multisystem Inflammatory Disorder In Children And Adolescents Paediatric Inflammatory Multisystemic Syndrome Mic
Postinflammatory Pulmonary Fibrosis	Post-Inflammatory Pulmonary Fibrosis
Adult Respiratory Distress Syndrome	Acute Respiratory Distress Syndrome Ards Non-Cardiogenic Pulmonary Edema Acute Lung Injury Respiratory Distress Syndrome, Adult Shock Lung Acute Respiratory Distress Respiratory Distress Syndrome Adult Rds Ali Increased-Permeability Pulmonary Edema Stiff Lung Respiratory Distress Syndrome Adult
Diabetes Mellitus, Ketosis-Prone	Diabetic Ketoacidosis KPD Diabetes Mellitus, Ketosis-Prone, Susceptibility To Ketosis-Prone Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent Diabetic Ketoacidosis Nos Dka - [Diabetic Ketoacidosis] Nos Dka - [Diabetic Ketoacidosis] Without Coma Dka - [Diabetic Ketoacidosis] With Coma
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Parotid Disease	Parotid Diseases
Mucormycosis	Zygomycosis Disseminated Mucormycosis Absidia Infection Absidia Mucoromycosis Cunninghamella Infection Cunninghamella Mucoromycosis Infection By Absidia Spp Infection By Rhizopus Spp Mucor Infection Mucor Mucoromycosis Infection By Mucor Spp Rhizopus Infection Rhizopus Mucoromycosis Infection By Cunninghamella Spp Phycomycosis Nos
Marburg Hemorrhagic Fever	Marburg Virus Disease Marburg Disease Green Monkey Disease Mhf Vervet Monkey Disease Mard - [Marburg Disease] Mvd - [Marburg Virus Disease] Marburg Haemorrhagic Fever Mhf - [Marburg Haemorrhagic Fever]
Geographic Tongue	Benign Migratory Glossitis Glossitis Areata Exfoliativa Glossitis, Benign Migratory Pityriasis Linguae Ectopic Geographic Tongue Erythema Migrans Erythema Chronicum Migrans Benign Migrating Glossitis Geographical Tongue Lingua Geographica Erythema Migrans Of Tongue Wandering Rash Of Tongue
Lymph Node Disease	Abnormality Of The Lymph Nodes Disorder Of Lymph Node
Bacterial Pneumonia	Gram-Negative Pneumonia Pneumonia Due To Other Gram-Negative Bacteria Pneumonia Bacterial Pneumonia, Bacterial Acute Bacillus Pneumonia Acute Bacterial Pneumonia Bacillus Double Pneumonia Bacillus Pneumonia Bacteria Pneumonia Bacterial Double Pneumonia Bacterial Lobar Pneumonia Bacterial Purulent Pneumonia Bronchopneumonia Due To Bacteria Other Than S. Pneumoniae And H. Influenzae
Pityriasis Rosea	Pityriasis Circinata Gibert Pityriasis
Acute Inferolateral Myocardial Infarction	Acute Myocardial Infarction Of Inferolateral Wall
Disease By Infectious Agent	Infectious Disease Infectious Diseases
Cavernous Sinus Thrombosis	Thrombosis Of Cavernous Venous Sinus
Intracranial Sinus Thrombosis	Sinus Thrombosis, Intracranial
Postencephalitic Parkinson Disease	Postencephalitic Parkinsonism Parkinson Disease, Postencephalitic
Pericardial Effusion	Noninflammatory Pericardial Effusion Pericardium Effusion
Salivary Gland Disease	Salivary Gland Disorders Salivary Gland Diseases Non-Neoplastic Salivary Gland Disease Non-Neoplastic Salivary Gland Disorder Disorder Of Salivary Gland Lesion Of Salivary Gland Nos
Respiratory Failure	Acute Respiratory Failure Chronic Respiratory Failure Respiratory Insufficiency Acute-On-Chronic Respiratory Failure Respiratory Disease Acute And Chronic Respiratory Failure Respiratory Insufficiency/Failure Chronic Respiratory Disease Pulmonary Valve Insufficiency Chronic Disease Of Respiratory System Respiration Disorders Respiratory Tract Diseases Lung Failure Nos Pulmonary Failure Arf - [Acute Respiratory Failure] Acute Respiratory Insufficiency Acute Pulmonary Insufficiency Acute Respiration Failure Chronic Respiration Failure
Facial Nerve Disease	Facial Nerve Disorder Facial Nerve Diseases Neuropathy Of Facial Nerve Disorders Of 7th Cranial Nerve Disorders Of The Seventh Cranial Nerve
Ischemic Colitis	Colitis, Ischemic Irreversible Ischaemic Colitis
Atrophic Glossitis	Atrophy Of Tongue Papillae Glossitis, Hunter'S Hunter'S Glossitis Smooth Atrophic Tongue Hunter Glossitis Central Papillary Atrophy Of The Tongue
Facial Paralysis	Facial Palsy Bell Palsy
Autoimmune Disease Of Peripheral Nervous System
Heart Aneurysm	Cardiac Aneurysm
Myelitis	Spinal Cord Inflammation Nos Radiculomyelitis Nos Myeloradiculitis
Coronary Aneurysm	Aneurysm Of Coronary Vessels Aneurysmal Lesion Of Coronary Artery Arteriovenous Aneurysm Of Coronary Vessels
Viral Laryngitis
Lassa Fever	Lf Lassa Hemorrhagic Fever Lf - [Lassa Fever]
Blood Coagulation Disease	Blood Coagulation Disorders Coagulation Protein Disease Inherited Blood Coagulation Disease Postpartum Coagulation Defect Postpartum Coagulation Defect With Delivery Coagulation Protein Disorders Puerperal Coagulopathy
Androgenic Alopecia	Androgenetic Alopecia Alopecia Androgenetica, Male Pattern Baldness
Nasal Cavity Disease	Disorder Of Nasal Cavity
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Pericarditis
Aspiration Pneumonia	Pneumonia, Aspiration Pneumonia Aspiration Aspiration Pneumonitis
Hemophagocytic Lymphohistiocytosis	Lymphohistiocytosis, Hemophagocytic Haemophagocytic Syndrome Lymphohistiocytosis Hemophagocytic Hemophagocytic Syndrome Familial Hemophagocytic Lymphocytosis Histiocytoses Of Mononuclear Phagocytes Haemophagocytic Lymphohistiocytosis Nos
Bacterial Sepsis
Nose Disease	Nose Diseases Disorder Of The Nose Nasal Disorder Abnormality Of The Nose
Plague	Yersiniosis Yersinia Infections Infection By Yersinia Pestis Pasteurella Pestis Infection Pestilential Fever Yersinia Pestis Infection
Poliomyelitis	Polio Infantile Paralysis
Laryngitis	Acute Laryngitis
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Swine Influenza	Influenza Due To Influenza A Virus Subtype H1n1
Cecal Disease	Cecal Diseases Disorder Of Cecum
Amebiasis	Amoebiasis Entamoebiasis Chronic Intestinal Amebiasis Amoebiasis, Unspecified Amebic Colitis Amoebic Enteritis Infection Due To Entamoeba Histolytica Amoebic Infection Disease Due To Endamoebidae Amoebiasis Nos
Telogen Effluvium
Retinitis Pigmentosa 40	RP40 Retinitis Pigmentosa-40 Retinitis Pigmentosa, Type 40
Testicular Disease	Testicular Dysfunction Testicular Diseases Disorder Of Testis Testis Disorder Testicular Disorders
Meningoencephalitis	Acquired Toxoplasmal Meningoencephalitis Meningoencephalitis Due To Acquired Toxoplasmosis Meningoencephalitis Due To Toxoplasmosis Toxoplasma Meningoencephalitis
Epididymis Disease
Central Nervous System Origin Vertigo	Vertigo Of Central Origin Vertigo Central Vestibular Vertigo
Bronchial Disease	Bronchial Diseases Bronchial Disorders Bronchial Spasm
Diabetes Mellitus	Diabetes
Parasitic Protozoa Infectious Disease	Protozoan Infections Mastigophora Infectious Disease Sarcomastigophora Infectious Disease
Leukocyte Disease	Leukocyte Disorders
Blood Platelet Disease	Platelet Disorder Blood Platelet Disorders Thrombocytopathy Platelet Dysfunction Platelet Disorders Qualitative Platelet Deficiency
Stroke, Ischemic	Cerebral Infarction Stroke Ischemic Stroke Cerebrovascular Accident Cerebral Infarction, Susceptibility To Stroke, Ischemic, Susceptibility To Cerebral Infarct Ischemic Stroke, Susceptibility To Stroke, Susceptibility To Cva - Cerebral Infarction ISCHSTR Ischemic Cerebrovascular Accident
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Pulmonary Disease, Chronic Obstructive	Chronic Obstructive Pulmonary Disease COPD Pulmonary Disease, Chronic Obstructive, Severe Early-Onset Chronic Obstructive Lung Disease Chronic Obstructive Airway Disease Pulmonary Disease, Chronic Obstructive, Susceptibility To Cold Severe Early-Onset Chronic Obstructive Pulmonary Disease Pulmonary Disease Chronic Obstructive Pulmonary Disease, Obstructive, Chronic, Susceptibility To Chronic Obstructive Pulmonary Disease Of Horses Common Cold Upper Respiratory Infections Copd - [Chronic Obstructive Pulmonary Disease] Coad - [Chronic Obstructive Airways Disease] Cold - [Chronic Obstructive Lung Disease] Chronic Airway Disease Nos Chronic Airways Limitation, Unspecified Chronic Obstructed Airway, Unspecified Chronic Obstructive Airway Disease, Unspecified Chronic Obstructive Airway, Unspecified Obstructive Lung Disease Nos Chronic Obstructive Lung Disease Nos Chronic Obstructive Lung Nos Obstructive Pulmonary Disease Nos Exacerbation Copd Nos Acute Exacerbation Copd
Heart Conduction Disease	Conduction Disorder Of The Heart Heart Rhythm Disease
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To Cryptogenic Fibrosing Alveolitis ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Patent Foramen Ovale	Atrial Septal Defect Within Oval Fossa Foramen Ovale Patent Ostium Secundum Atrial Septal Defect Atrial Septal Defect, Ostium Secundum Type Foramen Ovale, Patent Defect, Patent Or Persistent, Ostium Secundum Ostium Secundum Type Atrial Septal Defect Persistent Ostium Secundum Asd Ostium Secundum Type Ostium Secundum Asd Osasd Asd, Ostium Secundum Type Pfo - [Patent Foramen Ovale] Open Foramen Ovale Open Oval Foramen Persistent Foramen Ovale Secundum Atrial Septal Defect
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset Obesity , Susceptibility To BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ACE2	VGNC	VGNC:25535
Rattus norvegicus	ACE2	RGD	RGD:728890
Canis familiaris	ACE2	VGNC	VGNC:37503
Felis catus	ACE2	VGNC	VGNC:59506
Macaca mulatta	ACE2	VGNC	VGNC:78431
Mus musculus	ACE2	MGD	MGI:1917258
Others	ACE2	NCBI