(R)-MLN-4760
Based on 1 Customer Validation
(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer.
For research use only. We do not sell to patients.
- Purity: 99.51%
- CAS No.: 305335-29-9
- Formula: C19H23Cl2N3O4
- Molecular Weight:428.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
IC50: 8.4 nM (ACE2)[1]
(R)-MLN-4760 (compound 16RS) is the less active isomer of MLN-4760[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 305335-29-9
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Appearance Solid
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Molecular Weight 428.31
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Formula C19H23Cl2N3O4
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Color White to off-white
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SMILES
O=C(O)[C@H](CC1=CN=CN1CC2=CC(Cl)=CC(Cl)=C2)N[C@@H](C(O)=O)CC(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 14.29 mg/mL (33.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3348 mL | 11.6738 mL | 23.3476 mL | 58.3689 mL |
| 5 mM | 0.4670 mL | 2.3348 mL | 4.6695 mL | 11.6738 mL | |
| 10 mM | 0.2335 mL | 1.1674 mL | 2.3348 mL | 5.8369 mL | |
| 15 mM | 0.1557 mL | 0.7783 mL | 1.5565 mL | 3.8913 mL | |
| 20 mM | 0.1167 mL | 0.5837 mL | 1.1674 mL | 2.9184 mL | |
| 25 mM | 0.0934 mL | 0.4670 mL | 0.9339 mL | 2.3348 mL | |
| 30 mM | 0.0778 mL | 0.3891 mL | 0.7783 mL | 1.9456 mL |