CK2-IN-15
CK2-IN-15 (Compound Biv5) is a selective and potent bivalent protein kinase CK2 inhibitor with an IC50 value of 51 pM. CK2-IN-15 significantly reduces the replication of SARS-CoV-2 in HEK-ACE2-TMPRSS2 and Vero cells, and also reduces viral replication in an ex vivo model of human nasal epithelial cells. CK2-IN-15 is promising for research of β-coronavirus infection-related diseases.
For research use only. We do not sell to patients.
- Formula: C34H35ClN4O2
- Molecular Weight:567.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CK2α 51 pM (IC50) |
Chemical Information
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Molecular Weight 567.12
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Formula C34H35ClN4O2
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SMILES
O=C(C1=CC=C2C(N=C(NCCCCCCCCNCC3=CC=C(C4=CC=CC=C4)C(Cl)=C3)C5=C2C=NC=C5)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)