2. Recombinant Proteins
  3. Viral Proteins
  4. SARS-CoV-2 Proteins
  5. SARS-CoV-2 Spike Proteins
  6. SARS-CoV-2 S Protein

SARS-CoV-2 S Protein

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72035
    SARS-CoV-2 S glycoprotein (HEK293, His, Flag)

    E2 Peplomer protein

    		Virus HEK293
    The SARS-CoV-2 S glycoprotein is critical in infection, binding to the ACE2 receptor and allowing viral particles to attach to the host cell membrane. Cleavage of S2/S2′ triggers cell membrane fusion or internalization via endocytosis. SARS-CoV-2 S glycoprotein (HEK293, His, Flag) is the recombinant Virus-derived SARS-CoV-2 S glycoprotein, expressed by HEK293 , with N-10*His, C-Flag labeled tag. The total length of SARS-CoV-2 S glycoprotein (HEK293, His, Flag) is 670 a.a., with molecular weight of ~120 kDa.
  • HY-P72038
    SARS-CoV-2 S glycoprotein (HEK293, His-mFc)

    Spike glycoproteinRBD; ,Spike Protein RBD;

    		Virus HEK293
    The SARS-CoV-2 S glycoprotein is critical in infection, binding to the ACE2 receptor and allowing viral particles to attach to the host cell membrane. Cleavage of S2/S2′ triggers cell membrane fusion or internalization via endocytosis. SARS-CoV-2 S glycoprotein (HEK293, His-mFc) is the recombinant Virus-derived SARS-CoV-2 S glycoprotein, expressed by HEK293 , with C-mFc, C-6*His labeled tag. The total length of SARS-CoV-2 S glycoprotein (HEK293, His-mFc) is 223 a.a., with molecular weight (glycosylation form) of ~66.0 kDa.
  • HY-P72045
    SARS-CoV S Protein (HEK293, His-Myc)

    S glycoprotein; E2; Peplomer protein; Spike protein S1; Spike protein S2;

    		Virus HEK293
    The SARS-CoV S protein coordinates viral entry by interacting with human ACE2 and CLEC4M/DC-SIGNR receptors to attach viral particles to the cell membrane. It downregulates host tethering protein (BST2) through lysosomal degradation, antagonizing its antiviral activity. SARS-CoV S Protein (HEK293, His-Myc) is the recombinant Virus-derived SARS-CoV S protein, expressed by HEK293 , with N-10*His, C-Myc labeled tag. The total length of SARS-CoV S Protein (HEK293, His-Myc) is 222 a.a., with molecular weight of ~37 kDa.
  • HY-P74444
    SARS-CoV-2 S Protein (Omicron, B.1.1.529, His)

    SARS-CoV-2 Protein; SARS-CoV-2 Spike Protein

    		Virus HEK293
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (Omicron, B.1.1.529, His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by HEK293 , with C-His labeled tag. SARS-CoV-2 S Protein (Omicron, B.1.1.529, His), has molecular weight of ~136.67 kDa.
  • HY-P72036
    SARS-CoV-2 S glycoprotein (D614G, HEK293, His)

    E2 Peplomer protein

    		Virus HEK293
    SARS-CoV-2 S glycoprotein (D614G, HEK 293, His) is a SARS-CoV-2 S glycoprotein D614G protein with a His-flag. SARS-CoV-2 S glycoprotein (D614G) is a SARS-CoV-2 variant carrying the S protein amino acid (aa) change D614G, this variant has become the most prevalent form and has been associated with greater infectivity.
  • HY-P72039
    SARS-CoV-2 S glycoprotein (HEK293, His-Myc)

    S glycoprotein; E2; Peplomer protein

    		Virus HEK293
    The SARS-CoV-2 S glycoprotein is critical in infection, binding to the ACE2 receptor and allowing viral particles to attach to the host cell membrane. Cleavage of S2/S2′ triggers cell membrane fusion or internalization via endocytosis. SARS-CoV-2 S glycoprotein (HEK293, His-Myc) is the recombinant Virus-derived SARS-CoV-2 S glycoprotein, expressed by HEK293 , with N-10*His, C-Myc labeled tag. The total length of SARS-CoV-2 S glycoprotein (HEK293, His-Myc) is 223 a.a., with molecular weight of ~30.1 kDa.
  • HY-P72042
    SARS-CoV-2 S glycoprotein (V483A, HEK293, His)

    E2 Peplomer protein

    		Virus HEK293
    SARS-CoV-2 S glycoprotein (V483A, HEK 293, His) is a recombinant protein expressed in HEK 293 cells with a His tag. S glycoprotein plays an important role in the evolution and transmission of SARS-CoV-2.
  • HY-P73392
    SARS-CoV S Protein (S577A, sf9, His)

    Spike glycoprotein; S glycoprotein; Peplomer protein; S

    		Virus Sf9 insect cells
    SARS-CoV spike glycoprotein 2 (S2) is a subunit of SARS-CoV Spike glycoprotein, among with S1 and S2'. S2 (668-1255) mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein, during endocytosis, S2 is cleaved into S2' (798-1255). Internalization into host cell endosomes induces S glycoprotein conformational changes, potentially unmasking the fusion peptide of S2 through cathepsin CTSL proteolysis. SARS-CoV S Protein (S577A, sf9, His) is the recombinant Virus-derived SARS-CoV S protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SARS-CoV S Protein (S577A, sf9, His) is 1195 a.a., with molecular weight of ~132.58 kDa.
  • HY-P72037
    SARS-CoV-2 S glycoprotein (P.pastoris, His, SUMO)

    Spike glycoprotein

    		Virus P. pastoris
    The SARS-CoV-2 S glycoprotein is critical in infection, binding to the ACE2 receptor and allowing viral particles to attach to the host cell membrane. Cleavage of S2/S2′ triggers cell membrane fusion or internalization via endocytosis. SARS-CoV-2 S glycoprotein (P.pastoris, His, SUMO) is the recombinant Virus-derived SARS-CoV-2 S glycoprotein, expressed by P. pastoris , with N-6*His, N-SUMO labeled tag. The total length of SARS-CoV-2 S glycoprotein (P.pastoris, His, SUMO) is 223 a.a., with molecular weight of ~38.2 kDa.
  • HY-P74578
    SARS-CoV-2 S Protein (sf9, His)

    SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD Protein; 2019-nCoV Spike Protein

    		Virus Sf9 insect cells
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (sf9, His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SARS-CoV-2 S Protein (sf9, His) is 1198 a.a., with molecular weight of ~134.36 kDa.
  • HY-P76630
    SARS-CoV-2 S Protein (D614G, sf9, His)

    SARS-CoV-2 (2019-nCoV) Spike Protein; 2019-nCoV Spike Protein

    		Virus Sf9 insect cells
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (D614G, sf9, His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SARS-CoV-2 S Protein (D614G, sf9, His) is 1213 a.a., with molecular weight of ~134.3 kDa.
  • HY-P76631
    SARS-CoV-2 S Protein (Mutated, HEK293, His)

    SARS-CoV-2 (2019-nCoV) Spike Protein; 2019-nCoV Spike Protein

    		Virus HEK293
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (Mutated, HEK293, His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by HEK293 , with C-His labeled tag. The total length of SARS-CoV-2 S Protein (Mutated, HEK293, His) is 1213 a.a., with molecular weight of ~138.5 kDa.
  • HY-P72040
    SARS-CoV-2 S glycoprotein (V367F, HEK293, His)

    E2 Peplomer protein

    		Virus HEK293
    SARS-CoV-2 S glycoprotein (V367F, HEK 293, His) is a SARS-CoV-2 S glycoprotein V367F protein with a His-flag. SARS-CoV-2 S glycoprotein (V367F) is a SARS-CoV-2 variant carrying the S protein amino acid (aa) change V367F. The mutant type V367F continuously circulating worldwide displays higher binding affinity to human ACE2 .
  • HY-P72041
    SARS-CoV-2 S glycoprotein (G476S, HEK293, His)

    E2 Peplomer protein

    		Virus HEK293
    SARS-CoV-2 S glycoprotein (G476S, HEK 293, His) is a SARS-CoV-2 S glycoprotein G476S protein with a His-flag. Variations at G476S alters the ACE2 binding affinity. G476S variants display reduced affinity to ACE2 in comparison to the Wuhan SARS-CoV2 spike protein.
  • HY-P77480
    SARS-CoV-2 S Protein (Biotinylated, sf9, Avi-His)

    SARS-CoV-2 (2019-nCoV) Spike S1+S2 Biotinylated Protein

    		Virus Sf9 insect cells
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (Biotinylated, sf9, Avi-His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by Sf9 insect cells , with C-Avi, C-His labeled tag. The total length of SARS-CoV-2 S Protein (Biotinylated, sf9, Avi-His) is 1213 a.a., with molecular weight of ~136.20 KDa.
  • HY-P76632
    SARS-CoV-2 S Protein (Biotinylated, sf9, His)

    SARS-CoV-2 (2019-nCoV) Spike Protein; 2019-nCoV Spike Protein

    		Virus Sf9 insect cells
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (Biotinylated, sf9, His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SARS-CoV-2 S Protein (Biotinylated, sf9, His) is 1198 a.a., with molecular weight of ~134.4 kDa.
Cat. No. Product Name Effect Purity