1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. Resorcinolnaphthalein

Resorcinolnaphthalein 

Cat. No.: HY-122445
Handling Instructions

Resorcinolnaphthalein is a specific angiotensin-converting enzyme 2 (ACE2) enhancer and activates ACE2 activity with an EC50 value of 19.5 μM. Resorcinolnaphthalein can be used for the investigation of hypertension and renal fibrosis.

For research use only. We do not sell to patients.

Resorcinolnaphthalein Chemical Structure

Resorcinolnaphthalein Chemical Structure

CAS No. : 41307-63-5

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Description

Resorcinolnaphthalein is a specific angiotensin-converting enzyme 2 (ACE2) enhancer and activates ACE2 activity with an EC50 value of 19.5 μM. Resorcinolnaphthalein can be used for the investigation of hypertension and renal fibrosis[1].

IC50 & Target

EC50: 19.5 μM (ACE2)[1]

In Vitro

Resorcinolnaphthalein (100 μM) and XNT enhances ACE2 activity in a dose-dependent manner with EC50 values of 19.5 μM and 20.1 μM, respectively[1].
ACE2 is an effective enzyme in attenuating fibrosis and structural remodeling. Enhancement of ACE2 activity has beneficial effects on the cardiovascular system and protects against hypertension induced pathophysiology[1].

Molecular Weight

382.36

Formula

C₂₄H₁₄O₅

CAS No.

41307-63-5

SMILES

O=C1C2=CC=CC3=C2C(C4(C5=C(OC6=C4C=CC(O)=C6)C=C(O)C=C5)O1)=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

ResorcinolnaphthaleinAngiotensin-converting Enzyme (ACE)ACE2hypertensionrenalfibrosisreversalmyocardialperivascularInhibitorinhibitorinhibit

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Resorcinolnaphthalein
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