SARS-CoV-2 PLpro-IN-2
SARS-CoV-2 PLpro-IN-2 (Compound 12) is a highly selective SARS-CoV-2 papain-like protease (PLpro) inhibitor of (IC50=0.06 μM). SARS-CoV-2 PLpro-IN-2 inhibits viral replication and immune evasion. SARS-CoV-2 PLpro-IN-2 exhibits antiviral efficacy in HeLa-ACE2 cells (EC50=2.9 μM). SARS-CoV-2 PLpro-IN-2 is promising for research of COVID-19.
For research use only. We do not sell to patients.
- CAS No.: 1581755-42-1
- Formula: C25H27ClN2O
- Molecular Weight:406.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1581755-42-1
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Molecular Weight 406.95
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Formula C25H27ClN2O
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SMILES
C[C@@H](N1CCC(C(NCC2=CC=C(Cl)C=C2)=O)CC1)C3=CC=CC4=CC=CC=C43
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)