AG-2 Protein, Mouse (His)

AG-2 protein is a member of the protein disulfide isomerase family and is predicted to bind to dystroglycan, epidermal growth factor receptor, and the same proteins. It plays a role in digestive tract morphogenesis, mucus secretion, and developmental growth regulation. AG-2 Protein, Mouse (His) is the recombinant mouse-derived AG-2 protein, expressed by E. coli , with C-His labeled tag. The total length of AG-2 Protein, Mouse (His) is 155 a.a., with molecular weight of 18.82 kDa.

AG-2, encoding for Anterior Gradient 2, a member of the protein disulfide isomerase family, is anticipated to exhibit dystroglycan binding activity, epidermal growth factor receptor binding activity, and identical protein binding activity. This protein is implicated in diverse biological processes, including digestive tract morphogenesis, mucus secretion, and positive regulation of developmental growth. AG-2 is positioned in the endoplasmic reticulum and displays biased expression in various tissues, with notable prevalence in the large intestine and colon of adults. The orthologous relationship to the human AGR2 underscores its evolutionary conservation, suggesting shared functional roles and potential contributions to cellular and developmental processes.

Mouse

E. coli

C-His

NP_035913.1 (K21-L175)

23795  [NCBI]

18.82 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.