Agr2 - anterior gradient 2 Gene

Also Known as Agr2h; Gob-4; HAG-2; XAG-2; mAG-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23795

Summary

Predicted to enable dystroglycan binding activity; epidermal growth factor receptor binding activity; and identical protein binding activity. Involved in digestive tract morphogenesis; mucus secretion; and positive regulation of developmental growth. Acts upstream of or within lung goblet cell differentiation. Located in endoplasmic reticulum. Is expressed in several structures, including eye; genitourinary system; gut; liver; and lung. Orthologous to human AGR2 (anterior gradient 2, protein disulphide isomerase family member). [provided by Alliance of Genome Resources, Apr 2022]

Agr2 Products (1)

mRNA Protein Name
NM_011783.2 NP_035913.1 anterior gradient protein 2 homolog precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31040128 MGI
Biological Process GO Annotation Evidence References Source
involved in digestive tract morphogenesis IMP
IMP: Inferred from mutant phenotype
25666625 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
31040128 MGI
acts upstream of or within lung goblet cell differentiation IDA
IDA: Inferred from direct assay
22675208 MGI
acts upstream of or within mucus secretion IMP
IMP: Inferred from mutant phenotype
19359471 MGI
involved in mucus secretion IMP
IMP: Inferred from mutant phenotype
19359471 MGI
involved in positive regulation of developmental growth IMP
IMP: Inferred from mutant phenotype
25666625 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
19359471 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anterior gradient protein 2 homolog

  • AG-2

  • anterior gradient 2 homolog

  • protein Gob-4

  • secreted cement gland protein XAG-2 homolog

Recombinant Agr2 Proteins

Cat. No. Product Name Accession Purity
HY-P78771 AG-2 Protein, Mouse (HEK293, His) O88312 (K21-L175) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P701076 AG-2 Protein, Mouse (His) NP_035913.1 (K21-L175) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P5831 Biotin-H10 Inhibitor 98.94% Unkown
HY-RS00462 AGR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17048 Agr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23492 Agr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992187 Anti-AGR2 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agr2 NCBI NCBI:10551