1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Immunoglobulin-like Cell Adhesion Molecules
  5. Cell Adhesion Molecule 2 (CADM2)
  6. CADM2/IGSF4D Protein, Human (HEK293, His)

CADM2/IGSF4D Protein, Human (HEK293, His)

Cat. No.: HY-P75599
Handling Instructions

CADM2/IGSF4D, functioning as an adhesion molecule, facilitates homo- and heterophilic interactions with nectin-like family members, promoting cell aggregation. This protein is crucial for synapse organization and regulated trans-synaptic adhesion, displaying a preference for binding to oligodendrocytes and highlighting its role in cellular interactions within the nervous system. CADM2/IGSF4D Protein, Human (HEK293, His) is the recombinant human-derived CADM2/IGSF4D protein, expressed by HEK293, with C-His labeled tag. The total length of CADM2/IGSF4D Protein, Human (HEK293, His) is 306 a.a., with molecular weight of ~35.2 kDa.

For research use only. We do not sell to patients.

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Description

CADM2/IGSF4D, functioning as an adhesion molecule, facilitates homo- and heterophilic interactions with nectin-like family members, promoting cell aggregation. This protein is crucial for synapse organization and regulated trans-synaptic adhesion, displaying a preference for binding to oligodendrocytes and highlighting its role in cellular interactions within the nervous system. CADM2/IGSF4D Protein, Human (HEK293, His) is the recombinant human-derived CADM2/IGSF4D protein, expressed by HEK293, with C-His labeled tag. The total length of CADM2/IGSF4D Protein, Human (HEK293, His) is 306 a.a., with molecular weight of ~35.2 kDa.

Background

CADM2, also known as IGSF4D, serves as an adhesion molecule facilitating both homo- and heterophilic interactions with other members of the nectin-like family, thereby promoting cell aggregation. This protein holds significance in synapse organization, playing a crucial role in regulated trans-synaptic adhesion. Notably, CADM2 exhibits a preference for binding to oligodendrocytes, emphasizing its involvement in cellular interactions within the nervous system.

Species

Human

Source

HEK293

Tag

C-His

Accession

Q8N3J6 (G30-D335)

Gene ID
Molecular Construction
N-term
CADM2 (G30-D335)
Accession # Q8N3J6
His
C-term
Synonyms
Cell adhesion molecule 2; NECL-3; SynCAM 2; IGSF4D
Molecular Weight

Approximately 35.2 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CADM2/IGSF4D Protein, Human (HEK293, His)
Cat. No.:
HY-P75599
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