CD160 Protein, Rhesus Macaque (HEK293)

CD160 Protein, a member of the immunoglobulin 'superfamily' of proteins that binds weakly to MHC I and stimulates NK and CD8⁺ T‐cell activation^[1]. CD160 Protein, Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived CD160 protein, expressed by HEK293 , with tag free. The total length of CD160 Protein, Rhesus Macaque (HEK293) is 158 a.a., with molecular weight of ~15.6 KDa.

CD160, a 27 kDa glycoprotein, is a member of the immunoglobulin 'superfamily' of proteins. CD160 was initially identified with the monoclonal antibody BY55. CD160 is reported to be expressed by NK cells, NKT cells, intraepithelial T cells, γδ TCR⁺ T cells, and memory-phenotype, activated and effector CD8⁺ T cells. CD160 binds weakly to MHC I and stimulates NK and CD8⁺ T‐cell activation. CD160 also can act as a marker for cytolytic or exhausted CD8⁺ T cells. Such effects have been attributed to the ability of CD160 to bind classical and nonclassical MHC class I molecules, although with apparent low affinity, requiring clustering of MHC class I molecules or overexpression of CD160 or MHC class I for detection of the interaction^[1].

Rhesus Macaque

HEK293

Tag Free

G7MG20 (M1-L158)

696832  [NCBI]

Approximately 15.6 kDa.

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.