2. Recombinant Proteins
  3. Enzymes & Regulators Kinases
  4. Transferases (EC 2) Serine/Threonine Kinase Proteins CMGC
  5. Cyclin-Dependent Kinases (CDKs) CDK
  6. CDK11A/CDC2L2
  7. CDK11A Protein, Human (sf9, GST)

CDK11A Protein, Human (sf9, GST) is the recombinant human-derived CDK11A, expressed by Sf9 insect cells , with GST labeled tag.

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Beschreibung

CDK11A Protein, Human (sf9, GST) is the recombinant human-derived CDK11A, expressed by Sf9 insect cells , with GST labeled tag.
Background

CDK11A-CCND3 appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms are suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7, while the p58 isoform may act as a negative regulator of normal cell cycle progression. by similar: Other CDK family members are also involved in cell cycle regulation, but the splicing regulatory function of CDK11A-CCND3 is relatively unique.
Species

Human
Source

Sf9 insect cells
Tag

GST
Accession

Q9UQ88-1 (P361-F783)
Gene ID

728642
Protein Length

Partial
Synonyms
CDC2L2; CDC2L3; PITSLREB; Cyclin-dependent kinase 11A
AA Sequence

PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF

Predicted Molecular Mass
70 kDa
Reinheit

≥ 85%, as determined by reducing SDS-PAGE.
Dokumentation
Handling Instructions (2659 KB)

CDK11A Protein, Human (sf9, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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