CDO Protein, Human (HEK293, His)
CDO is an important component of cell surface receptor complexes and plays a key role in promoting intercellular interactions between muscle precursor cells and promoting the differentiation of myogenic cells. This receptor complex includes BOC, CDON, NEO1, cadherin and CTNNB1, which together coordinate complex signaling pathways necessary for cell development. CDO Protein, Human (HEK293, His) is the recombinant human-derived CDO protein, expressed by HEK293 , with C-His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
CDO is an important component of cell surface receptor complexes and plays a key role in promoting intercellular interactions between muscle precursor cells and promoting the differentiation of myogenic cells. This receptor complex includes BOC, CDON, NEO1, cadherin and CTNNB1, which together coordinate complex signaling pathways necessary for cell development. CDO Protein, Human (HEK293, His) is the recombinant human-derived CDO protein, expressed by HEK293 , with C-His labeled tag.
Background
CDO (Cell Adhesion Molecule-Related/Downregulated by Oncogenes) is a component of a cell-surface receptor complex crucial for mediating cell-cell interactions among muscle precursor cells. It plays a significant role in promoting the differentiation of myogenic cells. CDO is part of a complex that includes BOC, CDON, NEO1, cadherins, and CTNNB1, underscoring its involvement in intricate signaling networks. Additionally, CDO interacts with NTN3, PTCH1, and GAS1, suggesting its association with various signaling pathways. Notably, CDO engages with important signaling molecules such as DHH, IHH, and SHH, emphasizing its participation in pathways critical for cellular development and tissue patterning. The multifaceted interactions of CDO highlight its role as a key regulator in coordinating cellular processes during development. (
Technical Parameters
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Species Human
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Source HEK293
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Tag C-His
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Accession
Q4KMG0-1 (D26-D963)
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Molecular Construction
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N-term
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CDO (D26-D963)
Accession # Q4KMG0-1 -
His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
CDON; Ihog; Cell Adhesion Associated, Oncogene Regulated; Surface Glycoprotein, Ig Superfamily Member; Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes; Cdon Homolog (Mouse); CDO; Cdon Homolog; ORCAM; HPE11; CDON1
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AA Sequence
DLAPYFTSEPLSAVQKLGGPVVLHCSAQPVTTRISWLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMVVPFETNTKAETVTLPDAAQNDDRSKRDGSETGLLSSFPVKVHPSAVESAPEKNASGISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGVPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPVKDLSTPPNSLGSGGNVGPATSPARSSD
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Predicted Molecular Mass
103 kDa
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Molecular Weight
Approximately 125 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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