EPHA10 Protein, Human (HEK293, His)

The EPHA10 protein is a receptor for members of the ephrin A family and specifically interacts with EFNA3, EFNA4, and EFNA5. EPHA10 belongs to the Eph receptor tyrosine kinase family, mediates cellular responses to ephrin ligands, and affects processes such as cell adhesion, migration, and developmental patterns. EPHA10 Protein, Human (HEK293, His) is the recombinant human-derived EPHA10 protein, expressed by HEK293 , with C-His labeled tag.

EPHA10 Protein acts as a receptor for members of the ephrin-A family, specifically binding to EFNA3, EFNA4, and EFNA5. As a part of the Eph receptor tyrosine kinase family, EPHA10 is involved in mediating cellular responses to ephrin ligands, contributing to various physiological processes such as cell adhesion, migration, and developmental patterning. The interactions between EPHA10 and its ephrin ligands play a crucial role in orchestrating signaling events that regulate cellular behavior and contribute to the intricate molecular communication involved in development and tissue homeostasis.

Human

HEK293

C-8*His

Q5JZY3-1 (E34-A565)

284656  [NCBI]

Extracellular Domain

EEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPA

Approximately 60-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by Bis-Tris PAGE.

<1 EU/μg, determined by LAL method.