EPHA10 Protein, Human (HEK293, His)
The EPHA10 protein is a receptor for members of the ephrin A family and specifically interacts with EFNA3, EFNA4, and EFNA5. EPHA10 belongs to the Eph receptor tyrosine kinase family, mediates cellular responses to ephrin ligands, and affects processes such as cell adhesion, migration, and developmental patterns. EPHA10 Protein, Human (HEK293, His) is the recombinant human-derived EPHA10 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The EPHA10 protein is a receptor for members of the ephrin A family and specifically interacts with EFNA3, EFNA4, and EFNA5. EPHA10 belongs to the Eph receptor tyrosine kinase family, mediates cellular responses to ephrin ligands, and affects processes such as cell adhesion, migration, and developmental patterns. EPHA10 Protein, Human (HEK293, His) is the recombinant human-derived EPHA10 protein, expressed by HEK293 , with C-His labeled tag.
Background
EPHA10 Protein acts as a receptor for members of the ephrin-A family, specifically binding to EFNA3, EFNA4, and EFNA5. As a part of the Eph receptor tyrosine kinase family, EPHA10 is involved in mediating cellular responses to ephrin ligands, contributing to various physiological processes such as cell adhesion, migration, and developmental patterning. The interactions between EPHA10 and its ephrin ligands play a crucial role in orchestrating signaling events that regulate cellular behavior and contribute to the intricate molecular communication involved in development and tissue homeostasis.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-8*His
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Accession
Q5JZY3-1 (E34-A565)
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Molecular Construction
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N-term
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EPHA10 (E34-A565)
Accession # Q5JZY3-1 -
8*His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
EPHA10; FLJ33655; EPH Receptor A10; EphA10s Protein; Ephrin Type-A Receptor 10; EPHA10 Protein; FLJ16103; DFNA88
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AA Sequence
EEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPA
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Predicted Molecular Mass
58.8 kDa
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Molecular Weight
Approximately 60-70 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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