1. Recombinant Proteins
  2. Fc Receptors
  3. Fc Receptor-like Proteins
  4. Fc Receptor Like 2 (FCRL2)
  5. FCRL2 Protein, Human (HEK293, His)

FCRL2 Protein, Human (HEK293, His)

Cat. No.: HY-P76924
COA Handling Instructions

The FCRL2 protein regulates normal and neoplastic B cell development and has been shown to be involved in complex processes that control B cell maturation. Its tyrosine-phosphorylated isoform 2 interacts with PTPN6, suggesting the existence of a signaling pathway and emphasizing the role of this protein in cellular regulation. FCRL2 Protein, Human (HEK293, His) is the recombinant human-derived FCRL2 protein, expressed by HEK293 , with C-His labeled tag. The total length of FCRL2 Protein, Human (HEK293, His) is 376 a.a., with molecular weight of ~42.5 KDa.

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Description

The FCRL2 protein regulates normal and neoplastic B cell development and has been shown to be involved in complex processes that control B cell maturation. Its tyrosine-phosphorylated isoform 2 interacts with PTPN6, suggesting the existence of a signaling pathway and emphasizing the role of this protein in cellular regulation. FCRL2 Protein, Human (HEK293, His) is the recombinant human-derived FCRL2 protein, expressed by HEK293 , with C-His labeled tag. The total length of FCRL2 Protein, Human (HEK293, His) is 376 a.a., with molecular weight of ~42.5 KDa.

Background

The FCRL2 protein appears to have a regulatory role in both normal and neoplastic B cell development, suggesting its involvement in the intricate processes governing B cell maturation and function. Particularly, the tyrosine-phosphorylated isoform 2 of FCRL2 is known to interact with PTPN6, indicating a potential signaling pathway and emphasizing the protein's role in cellular regulation. The specific mechanisms through which FCRL2 influences B cell development and its interaction with PTPN6 remain areas of interest, underscoring the protein's importance in immune system processes and its potential relevance in the context of B cell-related disorders.

Species

Human

Source

HEK293

Tag

C-His

Accession

Q96LA5/NP_110391.2 (L20-D395)

Gene ID
Molecular Construction
N-term
FCRL2 (L20-D395)
Accession # Q96LA5/NP_110391.2
His
C-term
Synonyms
Fc receptor-like protein 2; FcRH2; CD307b; IFGP4; IRTA4; SPAP1
Molecular Weight

Approximately 42.5 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Solution

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

FCRL2 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
FCRL2 Protein, Human (HEK293, His)
Cat. No.:
HY-P76924
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