Haptoglobin Protein, Rat (HEK293, His)

Haptoglobin Proteinas, a positive regulator of collagen fibrillogenesis, likely plays a crucial role in extracellular matrix organization and remodeling. Its involvement extends to positively regulating MAP-kinase activity, contributing to increased adipocyte proliferation and diminished differentiation. Haptoglobin may also serve as a positive regulator of NF-kappa-B activity in macrophages, enhancing inflammatory responsiveness. Additionally, it exhibits transcriptional repressor activity, suggesting its role in gene expression modulation. Haptoglobin Protein, Rat (HEK293, His) is the recombinant rat-derived Haptoglobin protein, expressed by HEK293, with C-His labeled tag. The total length of Haptoglobin Protein, Rat (HEK293, His) is 347 a.a., with molecular weight of ~38.1 kDa.

ACLP, functioning as a positive regulator of collagen fibrillogenesis, likely plays a crucial role in the organization and remodeling of the extracellular matrix. Its involvement extends to positively regulating MAP-kinase activity in adipocytes, contributing to increased adipocyte proliferation and diminished adipocyte differentiation. Furthermore, ACLP may serve as a positive regulator of NF-kappa-B activity in macrophages, facilitating the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), ultimately enhancing macrophage inflammatory responsiveness. Additionally, ACLP exhibits transcriptional repressor activity, suggesting its involvement in the modulation of gene expression.

Rat

HEK293

C-His

P06866 (M1-N347)

24464  [NCBI]

Approximately 38.1 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.