HYOU1 Protein, Human (HEK293, His)

The HYOU1 protein plays a crucial role in coordinating cytoprotective mechanisms in response to hypoxia, indicating its importance in cellular stress responses. It involves a potential molecular chaperone function and is actively involved in the protein folding process. HYOU1 Protein, Human (HEK293, His) is the recombinant human-derived HYOU1 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of HYOU1 Protein, Human (HEK293, His) is 305 a.a., with molecular weight of 65-75 kDa.

The HYOU1 protein is intricately involved in vital cytoprotective responses activated during oxygen deprivation, emphasizing its crucial role in cellular adaptation to hypoxic conditions. Additionally, HYOU1 may function as a molecular chaperone, contributing to protein folding processes. It is a component of a substantial chaperone multiprotein complex that includes DNAJB11, HSP90B1, HSPA5, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGGT1, and minimal amounts of ERP29, while CALR and CANX are either absent or present at very low levels within this complex. These findings highlight the significance of HYOU1 in orchestrating cellular responses to oxygen deprivation and its potential involvement in protein quality control mechanisms.

Human

HEK293

C-10*His

Q9Y4L1 (M695-L999)

10525  [NCBI]

MVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL

65-75 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.