icl1 Protein, Mycobacterium tuberculosis
icl1 Protein, Mycobacterium tuberculosis is the recombinant icl1, expressed by E. coli , with tag Free labeled tag.
- Species: Others
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
icl1 Protein, Mycobacterium tuberculosis is the recombinant icl1, expressed by E. coli , with tag Free labeled tag.
Background
icl1 is involved in the persistence and virulence of M. tuberculosis. It catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which serves as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. Additionally, it catalyzes the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation pathway).
Technical Parameters
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Species Others
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Source E. coli
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Tag Tag Free
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Accession
P9WKK6 (M1-H428)
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Gene ID45424429
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Protein Length
Full Length
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Synonyms
Isocitrate lyase 1; EC:4.1.3.1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC:4.1.3.30; icl1; MT0483
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AA Sequence
MSVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKCGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQFH
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Predicted Molecular Mass
47.3 kDa
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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