Integrin alpha 10 beta 1 Protein, Human (HEK293, His)

Integrin α-10/β-1 is a collagen-specific receptor that plays a crucial role in mediating cell interactions with the extracellular matrix. It consists of alpha-10 and beta-1 subunits, which stably associate to form a heterodimeric complex. Integrin alpha 10 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 10 beta 1 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha 10 beta 1 Protein, Human (HEK293, His), has molecular weight of 140-160 kDa (ITGA10) & 100-130 kDa (ITGB), respectively.

Integrin alpha-10/beta-1, a cell surface receptor, plays a pivotal role as a specific receptor for collagen, mediating cellular interactions with the extracellular matrix. This integrin functions as a heterodimer, consisting of an alpha-10 subunit and a beta-1 subunit. The alpha-10 subunit forms a crucial association with the beta-1 subunit, creating a stable heterodimeric complex. Through this interaction, Integrin alpha-10/beta-1 contributes to various cellular processes by facilitating adhesion and signaling events in response to collagen, thereby influencing crucial aspects of cell behavior and tissue organization. Unraveling the nuances of Integrin alpha-10/beta-1's interactions provides insights into its significance in mediating cell-matrix interactions and its potential implications in physiological and pathological contexts.

Human

HEK293

C-8*His

O75578-1 (F23-S1122)&P05556-1 (Q21-D728)

8515&3688

Approximately 130-160 kDa (ITGA10) & 110-120 kDa (ITGB1),based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.