KIAA1279 Protein, Human (sf9)
KIAA1279 protein is crucial for organizing axonal microtubules, vital for axonal outgrowth and maintenance in both the peripheral and central nervous systems. Interacting with key proteins like KIF1B and STMN2, it likely participates in molecular mechanisms associated with axonal transport and dynamics, emphasizing its significance in orchestrating intricate processes essential for nervous system development. KIAA1279 Protein, Human (sf9) is the recombinant human-derived KIAA1279 protein, expressed by Sf9 insect cells, with tag free.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
KIAA1279 protein is crucial for organizing axonal microtubules, vital for axonal outgrowth and maintenance in both the peripheral and central nervous systems. Interacting with key proteins like KIF1B and STMN2, it likely participates in molecular mechanisms associated with axonal transport and dynamics, emphasizing its significance in orchestrating intricate processes essential for nervous system development. KIAA1279 Protein, Human (sf9) is the recombinant human-derived KIAA1279 protein, expressed by Sf9 insect cells, with tag free.
Background
KIAA1279 protein is essential for the organization of axonal microtubules, playing a crucial role in axonal outgrowth and maintenance throughout both peripheral and central nervous system development. It engages in interactions with key proteins such as KIF1B, suggesting its involvement in molecular mechanisms associated with axonal transport and dynamics. Additionally, its interaction with STMN2 underscores its potential role in modulating microtubule dynamics, as STMN2 is known to regulate microtubule stability. These interactions emphasize the significance of KIAA1279 in orchestrating the intricate processes that underlie axonal development and maintenance in the nervous system.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Tag Free
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Accession
Q96EK5 (N-G&P, M1-T621)
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Molecular Construction
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N-term
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Gly-Pro
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(M1-T621)
Accession # Q96EK5 -
C-term
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Protein Length
Full Length
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Synonyms
KIFBP; TTC20; Prev. KIAA1279; KIF1 Binding Protein; Prev. KIF1BP; KIF1-Binding Protein; KBP; DKFZP586B0923; KIF-Binding Protein; Mutant KIF1 Binding Protein; Kinesin Family Binding Protein; Kinesin Binding Protein
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Predicted Molecular Mass
72 kDa
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Molecular Weight
Approximately 72 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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