KIFBP - kinesin family binding protein Gene

Also Known as KBP; TTC20; KIF1BP; KIAA1279

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 26128

Summary

This gene encodes a Kinesin family member 1 binding protein that is characterized by two tetratrico peptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating transport of the mitochondria. Mutations in this gene are associated with Goldberg-Shprintzen megacolon syndrome. [provided by RefSeq, Mar 2010]

KIFBP Products (1)

mRNA Protein Name
XM_054365527.1 XP_054221502.1 KIF-binding protein isoform X1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables kinesin binding IPI
IPI: Inferred from physical interaction
16225668 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables protein sequestering activity IDA
IDA: Inferred from direct assay
33252036 GOA
Biological Process GO Annotation Evidence References Source
involved in mitochondrion transport along microtubule IMP
IMP: Inferred from mutant phenotype
16225668 GOA
involved in transport along microtubule IDA
IDA: Inferred from direct assay
33252036 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
16225668 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

KIF-binding protein

  • KIF1 binding protein

  • kinesin binding protein

  • mutant KIF1 binding protein

KIFBP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KIFBP Q96EK5 DCTN1 Homo sapiens Q14203-5
Validated Y2H
32814053
Intra
KIFBP Q96EK5 DCTN1 Homo sapiens Q14203-5
Y2H Array
32814053
Intra
KIFBP Q96EK5 DCTN1 Homo sapiens Q14203-5
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant KIFBP Proteins

Cat. No. Product Name Accession Purity
HY-P77039 KIAA1279 Protein, Human (sf9) Q96EK5 (N-G&P, M1-T621) ≥ 80%, as determined by reducing SDS-PAGE.
HY-P77040 KIAA1279 Protein, Human (sf9, His-GST) Q96EK5 (M1-T621) ≥ 90%, as determined by reducing SDS-PAGE.