KIAA1279 Protein, Human (sf9, His-GST)

KIAA1279 protein is crucial for organizing axonal microtubules, vital for axonal outgrowth and maintenance in both the peripheral and central nervous systems.Interacting with key proteins like KIF1B and STMN2, it likely participates in molecular mechanisms associated with axonal transport and dynamics, emphasizing its significance in orchestrating intricate processes essential for nervous system development.KIAA1279 Protein, Human (sf9, His-GST) is the recombinant human-derived KIAA1279 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

KIAA1279 protein is essential for the organization of axonal microtubules, playing a crucial role in axonal outgrowth and maintenance throughout both peripheral and central nervous system development. It engages in interactions with key proteins such as KIF1B, suggesting its involvement in molecular mechanisms associated with axonal transport and dynamics. Additionally, its interaction with STMN2 underscores its potential role in modulating microtubule dynamics, as STMN2 is known to regulate microtubule stability. These interactions emphasize the significance of KIAA1279 in orchestrating the intricate processes that underlie axonal development and maintenance in the nervous system.

Human

Sf9 insect cells

N-His;N-GST

Q96EK5 (M1-T621)

26128  [NCBI]

Full Length

MANVPWAEVCEKFQAALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPEAEDGPGAGDHALGLPAEVVEPEGPVAQRAVRLAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRRYRLSHDCISLCIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEVGSPPLDPTERFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHLEMFEKAAHYCHSTLKRQLEHNAYHPIEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT

Approximately 92-102 kDa,based on SDS-PAGE under reducing conditions.

≥ 90%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.