KIAA1279 Protein, Human (sf9, His-GST)
KIAA1279 protein is crucial for organizing axonal microtubules, vital for axonal outgrowth and maintenance in both the peripheral and central nervous systems.Interacting with key proteins like KIF1B and STMN2, it likely participates in molecular mechanisms associated with axonal transport and dynamics, emphasizing its significance in orchestrating intricate processes essential for nervous system development.KIAA1279 Protein, Human (sf9, His-GST) is the recombinant human-derived KIAA1279 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
KIAA1279 protein is crucial for organizing axonal microtubules, vital for axonal outgrowth and maintenance in both the peripheral and central nervous systems.Interacting with key proteins like KIF1B and STMN2, it likely participates in molecular mechanisms associated with axonal transport and dynamics, emphasizing its significance in orchestrating intricate processes essential for nervous system development.KIAA1279 Protein, Human (sf9, His-GST) is the recombinant human-derived KIAA1279 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
Background
KIAA1279 protein is essential for the organization of axonal microtubules, playing a crucial role in axonal outgrowth and maintenance throughout both peripheral and central nervous system development. It engages in interactions with key proteins such as KIF1B, suggesting its involvement in molecular mechanisms associated with axonal transport and dynamics. Additionally, its interaction with STMN2 underscores its potential role in modulating microtubule dynamics, as STMN2 is known to regulate microtubule stability. These interactions emphasize the significance of KIAA1279 in orchestrating the intricate processes that underlie axonal development and maintenance in the nervous system.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-His;N-GST
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Accession
Q96EK5 (M1-T621)
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Molecular Construction
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N-term
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His-GST
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KIAA1279 (M1-T621)
Accession # Q96EK5 -
C-term
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Protein Length
Full Length
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Synonyms
KIFBP; TTC20; Prev. KIAA1279; KIF1 Binding Protein; Prev. KIF1BP; KIF1-Binding Protein; KBP; DKFZP586B0923; KIF-Binding Protein; Mutant KIF1 Binding Protein; Kinesin Family Binding Protein; Kinesin Binding Protein
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AA Sequence
MANVPWAEVCEKFQAALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPEAEDGPGAGDHALGLPAEVVEPEGPVAQRAVRLAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRRYRLSHDCISLCIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEVGSPPLDPTERFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHLEMFEKAAHYCHSTLKRQLEHNAYHPIEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT
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Predicted Molecular Mass
99.6 kDa
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Molecular Weight
Approximately 92-102 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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