MLANA Protein, Human (His, B2M)

The MLANA protein is essential in melanosome biosynthesis, ensuring the stability of GPR143, and plays a key role in the expression, stability, transport, and processing of the melanocyte protein PMEL. Its interaction with PMEL and GPR143 highlights its integral role in the complex network required for second-stage melanosome formation. MLANA Protein, Human (His, B2M) is the recombinant human-derived MLANA protein, expressed by E. coli , with N-His, B2M labeled tag. The total length of MLANA Protein, Human (His, B2M) is 118 a.a., with molecular weight of ~27.2 kDa.

The MLANA protein is integral to melanosome biogenesis, ensuring the stability of GPR143 and playing a crucial role in the expression, stability, trafficking, and processing of the melanocyte protein PMEL. Its involvement in these processes is essential for the formation of stage II melanosomes. MLANA interacts with both PMEL and GPR143, establishing its role in the intricate network of protein interactions necessary for melanosome development. The coordination of these interactions underscores the significance of MLANA in melanocyte biology and the biogenesis of melanosomes.

Human

E. coli

N-His;B2M

Q16655 (1M-118P)

2315  [NCBI]

MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP

Approximately 27.2 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.