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NTNG1 Protein, Human (HEK293, His)

Cat. No.: HY-P71176
COA Handling Instructions

NTNG1, a master conductor in neural circuit development, intricately guides patterning across laminar, cellular, subcellular, and synaptic dimensions. Its influential role extends to fostering neurite outgrowth for axons and dendrites. In the symphony of neurodevelopment, NTNG1 interacts with NGL1, adding specificity to its involvement in shaping the intricate landscape of neuronal connectivity. NTNG1 Protein, Human (HEK293, His) is the recombinant human-derived NTNG1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of NTNG1 Protein, Human (HEK293, His) is 381 a.a., with molecular weight of ~51.0 kDa.

For research use only. We do not sell to patients.

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Description

NTNG1, a master conductor in neural circuit development, intricately guides patterning across laminar, cellular, subcellular, and synaptic dimensions. Its influential role extends to fostering neurite outgrowth for axons and dendrites. In the symphony of neurodevelopment, NTNG1 interacts with NGL1, adding specificity to its involvement in shaping the intricate landscape of neuronal connectivity. NTNG1 Protein, Human (HEK293, His) is the recombinant human-derived NTNG1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of NTNG1 Protein, Human (HEK293, His) is 381 a.a., with molecular weight of ~51.0 kDa.

Background

NTNG1 emerges as a master conductor in the orchestration of neural circuit development, intricately guiding patterning across laminar, cellular, subcellular, and synaptic dimensions. Its influential role extends to fostering the outgrowth of neurites, encompassing both axons and dendrites. In this symphony of neurodevelopment, NTNG1 engages in a nuanced interaction with NGL1, adding a layer of specificity to its involvement in shaping the intricate landscape of neuronal connectivity.

Species

Human

Source

HEK293

Tag

C-6*His

Accession

Q9Y2I2 (H29-S409)

Gene ID
Molecular Construction
N-term
NTNG1 (H29-S409)
Accession # Q9Y2I2
6*His
C-term
Synonyms
Netrin-G1; Laminet-1; NTNG1; KIAA0976; LMNT1
AA Sequence

HYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGS

Molecular Weight

Approximately 51.0 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of 20 mM Histidine-HCl, 6% Trehalose, 50 mM NaCl, 0.05% Tween 80, pH 5.0.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

NTNG1 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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NTNG1 Protein, Human (HEK293, His)
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HY-P71176
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